Evidence map›Paper›PMID 31662537›Full record

ArticleIn vivo (Athens, Greece)

Influence of Mixed Chimerism on Outcome in Children With Anaemia After Haematopoietic Stem Cell Transplantation.

Monika Lejman, Joanna Zawitkowska, Agnieszka Zaucha-Prażmo, Magdalena Cienkusz, Aleksandra Mroczkowska, Jerzy Kowalczyk, Katarzyna Drabko

Open access · diamondAbstract read
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 11 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Monika LejmanDepartment of Pediatric Hematology, Oncology and Transplantology, Medical University of Lublin, Laboratory of Genetic Diagnostics, Lublin, Poland lejmanm@poczta.onet.pl.
Joanna ZawitkowskaDepartment of Pediatric Hematology, Oncology and Transplantology, Medical University of Lublin, Lublin, Poland.
Agnieszka Zaucha-PrażmoDepartment of Pediatric Hematology, Oncology and Transplantology, Medical University of Lublin, Lublin, Poland.
Magdalena CienkuszDepartment of Pediatric Hematology, Oncology and Transplantology, Medical University of Lublin, Lublin, Poland.
Aleksandra MroczkowskaDepartment of Pediatric Hematology, Oncology and Transplantology, Medical University of Lublin, Lublin, Poland.
Jerzy KowalczykDepartment of Pediatric Hematology, Oncology and Transplantology, Medical University of Lublin, Lublin, Poland.
Katarzyna DrabkoDepartment of Pediatric Hematology, Oncology and Transplantology, Medical University of Lublin, Lublin, Poland.
Medical University of Lublin · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimIn patients with non-malignant diseases, mixed chimerism is not a rare phenomenon. The clinical impacts of chimerism following allogeneic haematopoietic stem cell transplantation (allo-HSCT) in children with congenital anaemia (CA) and severe aplastic anaemia (SAA) were analysed. PATIENTS AND

methodsWe studied twenty-seven consecutive children with congenital and acquired anaemia who had undergone allogeneic haematopoietic stem cell transplantations. In the observed group of patients, the median of the follow-up was 6.12 years (2.00-14.8 years).

resultsOverall survival (OS) did not depend on the type of disease p=0.1. OS did not significantly differ in patients who received more than 5x10

conclusionOur results showed that mixed chimerism did not influence the survival of children with congenital and aplastic anaemia following allo-HSCT.

Indexed as

Hematopoietic Stem Cell TransplantationTransplantation ChimeraAdolescentAnemiaChildChild, PreschoolCombined Modality TherapyFemaleFollow-Up StudiesHumansMaleTransplantation ConditioningTransplantation, HomologousTreatment OutcomeanaemiachildChimerismhaematopoietic stem cell transplantation

Identifiers

PMID31662537
PMCPMC6899150
OpenAlexW2984321141

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.