Evidence map›Paper›PMID 31662458›Full record

ArticlemBio2019

Shielding the Next Generation: Symbiotic Bacteria from a Reproductive Organ Protect Bobtail Squid Eggs from Fungal Fouling.

Allison H Kerwin, Samantha M Gromek, Andrea M Suria, Robert M Samples, Dister J Deoss, Kerry O'Donnell, Salvatore Frasca, Deanna A Sutton, Nathan P Wiederhold, Marcy J Balunas and 1 more

Open access · goldAbstract read
In one paragraph

Article in mBio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
8.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 52 citations in OpenAlex.

  1. Article
  2. Charting a Sustainable Course:Microorganisms · 2026
    Article
  3. Maintaining microbiota across diverse symbiotic organs inProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  4. Article
  5. Applied and environmental microbiology · 2025
    Article
  6. Host-Associated Biofilms:Microorganisms · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Transient infection ofApplied and environmental microbiology · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. The Life Cycle ofMicrobiology spectrum · 2023
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Allison H Kerwin *Department of Molecular and Cell Biology, University of Connecticut, Storrs, Connecticut, USA.
Samantha M Gromek *Division of Medicinal Chemistry, Department of Pharmaceutical Sciences, University of Connecticut, Storrs, Connecticut, USA.
Andrea M SuriaDepartment of Molecular and Cell Biology, University of Connecticut, Storrs, Connecticut, USA.
Robert M SamplesDivision of Medicinal Chemistry, Department of Pharmaceutical Sciences, University of Connecticut, Storrs, Connecticut, USA.
Dister J DeossDepartment of Molecular and Cell Biology, University of Connecticut, Storrs, Connecticut, USA.
Kerry O'DonnellMycotoxin Prevention and Applied Microbiology Research Unit, National Center for Agricultural Utilization Research, Agricultural Research Service, U.S. Department of Agriculture, Peoria, Illinois, USA.
Salvatore FrascaDepartment of Comparative, Diagnostic, and Population Medicine, College of Veterinary Medicine, University of Florida, Gainesville, Florida, USA.
Deanna A SuttonDepartment of Pathology and Laboratory Medicine, Fungus Testing Laboratory, University of Texas Health Science Center, San Antonio, Texas, USA.
Nathan P WiederholdDepartment of Pathology and Laboratory Medicine, Fungus Testing Laboratory, University of Texas Health Science Center, San Antonio, Texas, USA.
Marcy J BalunasDivision of Medicinal Chemistry, Department of Pharmaceutical Sciences, University of Connecticut, Storrs, Connecticut, USA marcy.balunas@uconn.edu spencer.nyholm@uconn.edu.
Spencer V NyholmDepartment of Molecular and Cell Biology, University of Connecticut, Storrs, Connecticut, USA marcy.balunas@uconn.edu spencer.nyholm@uconn.edu.
University of Connecticut · USThe University of Texas Health Science Center at San Antonio · USNational Center for Agricultural Utilization Research · USUniversity of Florida · US

Funding

SEEDING POSTDOCTORAL INNOVATORS IN RESEARCH &EDUCATIONK12GM000678 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DONALD T LYSLE, Kathryn Joanna Reissner · 1999 to 2026
$30.9M
NIGMS NIH HHS K12 GM000678
6 · The paper itself

Abstract

The importance of defensive symbioses, whereby microbes protect hosts through the production of specific compounds, is becoming increasingly evident. Although defining the partners in these associations has become easier, assigning function to these relationships often presents a significant challenge. Here, we describe a functional role for a bacterial consortium in a female reproductive organ in the Hawaiian bobtail squid,

Indexed as

Bacterial Physiological PhenomenaAnimal DiseasesAnimalsAntifungal AgentsBacteriaDecapodiformesEggsFemaleFungiFusariosisFusariumGenitaliaHawaiiHost Microbial InteractionsLincomycinMacrolidesAntifungal AgentsLincomycinMacrolidesmycinamicinschemical defensedefensive symbiosisEuprymna scolopeshost-microbe symbiosesinteraction-driven molecular networking

Identifiers

PMID31662458
PMCPMC6819662
OpenAlexW2982405210

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.