Evidence map›Paper›PMID 31662323›Full record

ArticleeNeuro

Identifying Parabrachial Neurons Selectively Regulating Satiety for Highly Palatable Food in Mice.

Erica Rodriguez, David Ryu, Shengli Zhao, Bao-Xia Han, Fan Wang

Open access · goldAbstract read
In one paragraph

Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
  3. Negative Emotions Recruit the Parabrachial Nucleus Efferent to the VTA to Disengage Instrumental Food Seeking.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Erica RodriguezDepartment of Neurobiology, Duke University Medical Center, Durham, NC 27708 er2934@cumc.columbia.edu.ORCID 0000-0001-5966-714X
David RyuDepartment of Neurobiology, Duke University Medical Center, Durham, NC 27708.
Shengli ZhaoDepartment of Neurobiology, Duke University Medical Center, Durham, NC 27708.
Bao-Xia HanDepartment of Neurobiology, Duke University Medical Center, Durham, NC 27708.
Fan WangDepartment of Neurobiology, Duke University Medical Center, Durham, NC 27708.ORCID 0000-0003-2988-0614
Duke University · US

Funding

Research Training in Mood and Anxiety Disorders: From Animal Models to PatientsT32MH015144 · NIMH · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Eduardo David Leonardo · 1985 to 2026
$11.1M
Toward causal neuroscience: capture and manipulate emergent neuronal ensemblesDP1MH103908 · NIMH · DUKE UNIVERSITY · PI WANG, FAN · 2013 to 2017
$3.9M
Functional Characterization of Parabrachial Circuits Processing Noxious Thermal PainF31DE025197 · NIDCR · DUKE UNIVERSITY · PI RODRIGUEZ, ERICA J · 2015 to 2017
$106k
NIDCR NIH HHS F31 DE025197NIMH NIH HHS DP1 MH103908NIMH NIH HHS T32 MH015144
6 · The paper itself

Abstract

Food consumption is necessary for organisms to maintain metabolic homeostasis. Both extrinsic and intrinsic processes, relayed via intricate neural circuitry, orchestrate the initiation and termination of food intake. More specifically, there are functionally distinct neural circuits that mediate either homeostatic or hedonic suppression of feeding. Notably, being satiated is a positive feeling whereas food aversion is a negative feeling. While significant progress has been made toward elucidating neural circuitry underlying aversive appetite suppression in mice, the circuitry underlying homeostatic satiety is not fully understood. The lateral parabrachial nucleus (PB

Indexed as

AnimalsEatingFeeding BehaviorFemaleFoodMaleMiceNeural PathwaysNeuronsParabrachial NucleusSatiationbrainstemFosnovel toolssatiety

Identifiers

PMID31662323
PMCPMC6868176
OpenAlexW2982625146

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.