Evidence map›Paper›PMID 31662055›Full record

ArticleToxicologic pathology2019

Insight and Resources From a Study of the "Impact of Sex, Androgens, and Prostate Size on C57BL/6J Mouse Urinary Physiology.

Hannah Ruetten, Kyle A Wegner, Helen L Zhang, Peiqing Wang, Jaskiran Sandhu, Simran Sandhu, Jacquelyn Morkrid, Brett Mueller, Zunyi Wang, Jill Macoska and 5 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxicologic pathology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. A uropathogenicAmerican journal of physiology. Renal physiology · 2021
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Hannah RuettenDepartment of Comparative Biosciences, University of Wisconsin-Madison, WI, USA.ORCID 0000-0001-6263-6221
Kyle A WegnerDepartment of Comparative Biosciences, University of Wisconsin-Madison, WI, USA.
Helen L ZhangDepartment of Comparative Biosciences, University of Wisconsin-Madison, WI, USA.
Peiqing WangDepartment of Comparative Biosciences, University of Wisconsin-Madison, WI, USA.
Jaskiran SandhuDepartment of Comparative Biosciences, University of Wisconsin-Madison, WI, USA.
Simran SandhuDepartment of Comparative Biosciences, University of Wisconsin-Madison, WI, USA.
Jacquelyn MorkridDepartment of Comparative Biosciences, University of Wisconsin-Madison, WI, USA.
Brett MuellerDepartment of Comparative Biosciences, University of Wisconsin-Madison, WI, USA.
Zunyi WangUniversity of Wisconsin-Madison/UMASS Boston George M. O'Brien Center for Benign Urologic Research, Madison, WI, and Boston, MA, USA.
Jill MacoskaUniversity of Wisconsin-Madison/UMASS Boston George M. O'Brien Center for Benign Urologic Research, Madison, WI, and Boston, MA, USA.
Richard E PetersonDivision of Pharmaceutical Sciences, University of Wisconsin-Madison, WI, USA.
Dale E BjorlingUniversity of Wisconsin-Madison/UMASS Boston George M. O'Brien Center for Benign Urologic Research, Madison, WI, and Boston, MA, USA.
William A RickeUniversity of Wisconsin-Madison/UMASS Boston George M. O'Brien Center for Benign Urologic Research, Madison, WI, and Boston, MA, USA.
Paul C MarkerUniversity of Wisconsin-Madison/UMASS Boston George M. O'Brien Center for Benign Urologic Research, Madison, WI, and Boston, MA, USA.
Chad M VezinaDepartment of Comparative Biosciences, University of Wisconsin-Madison, WI, USA.
University of Wisconsin–Madison · US

Funding

Viral VectorP30CA086862 · NCI · UNIVERSITY OF IOWA · PI Christopher K Laubenthal · 2000 to 2026
$70.0M
Role of Beta-Catenin in Urinary DysfunctionU54DK104310 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI RICKE, WILLIAM A · 2014 to 2023
$12.8M
NRSA Training CoreTL1TR002375 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI Vivek Prabhakaran · 2017 to 2026
$8.4M
REPRODUCTIVE AND DEVELOPMENTAL TOXICITY OF DIOXINR01ES001332 · NIEHS · UNIVERSITY OF WISCONSIN-MADISON · PI PETERSON, RICHARD EUGENE, VEZINA, CHAD M. · 1985 to 2021
$5.3M
Role of DNA methylation in prostate glandular development and urinary functionR01DK099328 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI VEZINA, CHAD M. · 2014 to 2018
$1.6M
Molecular and fate maps of prostatic stromaU01DK110807 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI VEZINA, CHAD M. · 2016 to 2020
$1.6M
Prostate inflammation increases collagen and voiding dysfunctionF30DK122686 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI RUETTEN, HANNAH MARGARET · 2019 to 2022
$157k
TCDD Reprograms Prostate Stroma and Causes Fibrosis to Induce Urinary DysfunctionF31ES028594 · NIEHS · UNIVERSITY OF WISCONSIN-MADISON · PI WEGNER, KYLE ALLEN · 2018 to 2019
$54k
NCATS NIH HHS TL1 TR002375NCI NIH HHS P30 CA086862NIDDK NIH HHS F30 DK122686NIDDK NIH HHS R01 DK099328NIDDK NIH HHS U01 DK110807NIDDK NIH HHS U54 DK104310NIEHS NIH HHS F31 ES028594NIEHS NIH HHS R01 ES001332
6 · The paper itself

Abstract

The purpose of this symposium report is to summarize information from a session 3 oral presentation at the Society of Toxicologic Pathology Annual Symposium in Raleigh, North Carolina. Mice are genetically tractable and are likely to play an important role in elucidating environmental, genetic, and aging-related mechanisms of urinary dysfunction in men. We and others have made significant strides in developing quantitative methods for assessing mouse urinary function and our collaborators recently showed that aging male mice, like men, develop urinary dysfunction. Yet, it remains unclear how mouse prostate anatomy and histology relate to urinary function. The purpose of this report is to share foundational resources for evaluating mouse prostate histology and urinary physiology from our recent publication "Impact of Sex, Androgens, and Prostate Size on C57BL/6J Mouse Urinary Physiology: Functional Assessment." We will begin with a review of prostatic embryology in men and mice, then move to comparative histology resources, and conclude with quantitative measures of rodent urinary physiology.

Indexed as

Urinary Tract Physiological PhenomenaAgingAndrogensAnimalsCongresses as TopicHumansMaleMiceMice, Inbred C57BLOrganogenesisOrgan SizeProstateSpecies SpecificityUrinary BladderAndrogenscystometrymouseprostateurinary systemvoid spot assay

Identifiers

PMID31662055
PMCPMC6910975
OpenAlexW2982658070

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.