Evidence map›Paper›PMID 31661879›Full record

ArticleBiomolecules2019

Structural Characterization of Full-Length Human Dehydrodolichyl Diphosphate Synthase Using an Integrative Computational and Experimental Approach.

Michal Lisnyansky Bar-El, Su Youn Lee, Ah Young Ki, Noa Kapelushnik, Anat Loewenstein, Ka Young Chung, Dina Schneidman-Duhovny, Moshe Giladi, Hadas Newman, Yoni Haitin

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

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  7. Structural elucidation of theProceedings of the National Academy of Sciences of the United States of America · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Michal Lisnyansky Bar-ElDepartment of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv 6997801, Israel. michallis505@gmail.com.
Su Youn LeeSchool of Pharmacy, Sungkyunkwan University, Jangan-gu, Suwon 16419, Korea. youn3887@hanmail.net.
Ah Young KiSchool of Pharmacy, Sungkyunkwan University, Jangan-gu, Suwon 16419, Korea. kay9039@naver.com.
Noa KapelushnikDepartment of Ophthalmology, Sheba Medical Center, Ramat Gan 5265601, Israel. kapelushniknoa@gmail.com.
Anat LoewensteinDepartment of Ophthalmology, Tel-Aviv Sourasky Medical Center, Tel Aviv 6423906, Israel. anatl@tlvmc.gov.il.
Ka Young ChungSchool of Pharmacy, Sungkyunkwan University, Jangan-gu, Suwon 16419, Korea. kychung2@gmail.com.
Dina Schneidman-DuhovnyDepartment of Biological Chemistry, Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem 9190401, Israel. dina.schneidman@mail.huji.ac.il.
Moshe GiladiDepartment of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv 6997801, Israel. moshegil@post.tau.ac.il.ORCID 0000-0002-8589-6920
Hadas NewmanDepartment of Ophthalmology, Tel-Aviv Sourasky Medical Center, Tel Aviv 6423906, Israel. hadasng@gmail.com.
Yoni HaitinDepartment of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv 6997801, Israel. yhaitin@tauex.tau.ac.il.
Sungkyunkwan University · KRTel Aviv University · ILTel Aviv Sourasky Medical Center · ILHebrew University of Jerusalem · ILSheba Medical Center · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dehydrodolichyl diphosphate synthase (DHDDS) is the catalytic subunit of the heteromeric human

Indexed as

Models, MolecularAlkyl and Aryl TransferasesAmino Acid SequenceHumansKineticsProtein MultimerizationProtein Structure, QuaternaryAlkyl and Aryl Transferasesdehydrodolichyl diphosphate synthetasecis-prenyltransferasecomputational modelingDHDDSenzyme kineticshydrogen–deuterium exchange mass-spectrometrysmall-angle X-ray scattering

Identifiers

PMID31661879
PMCPMC6921004
OpenAlexW2982071420

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.