Evidence map›Paper›PMID 31661787›Full record

ArticleHealthcare (Basel, Switzerland)2019

Cancer Survival Data Representation for Improved Parametric and Dynamic Lifetime Analysis.

Lode K J Vandamme, Peter A A F Wouters, Gerrit D Slooter, Ignace H J T de Hingh

Abstract read
In one paragraph

Article in Healthcare (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lode K J VandammeDepartment of Electrical Engineering, Eindhoven University of Technology, 5612AE Eindhoven, The Netherlands. l.k.j.vandamme@tue.nl.
Peter A A F WoutersDepartment of Electrical Engineering, Eindhoven University of Technology, 5612AE Eindhoven, The Netherlands. p.a.a.f.wouters@tue.nl.
Gerrit D SlooterDepartment of Surgical Oncology, Máxima Medical Center, 5504DB Veldhoven, The Netherlands. G.Slooter@mmc.nl.
Ignace H J T de HinghDepartment of Surgery, Catharina Hospital, 5623EJ Eindhoven, The Netherlands. Ignace.d.Hingh@catharinaziekenhuis.nl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Survival functions are often characterized by a median survival time or a 5-year survival. Whether or not such representation is sufficient depends on tumour development. Different tumour stages have different mean survival times after therapy. The validity of an exponential decay and the origins of deviations are substantiated. The paper shows, that representation of survival data as logarithmic functions visualizes differences better, which allows for differentiating short- and long-term dynamic lifetime. It is more instructive to represent the changing lifetime expectancy for an individual who has survived a certain time, which can be significantly different from the initial expectation just after treatment. Survival data from 15 publications on cancer are compared and re-analysed based on the well-established: (i) exponential decay (ii) piecewise constant hazard (iii) Weibull model and our proposed parametric survival models, (iv) the two-τ and (v) the sliding-τ model. The new models describe either accelerated aging or filtering out of defects with numerical parameters with a physical meaning and add information to the usually provided log-rank

Indexed as

cancer survival datadynamic lifetimehazard rateparametric survival modelstatistical distributions

Identifiers

PMID31661787
PMCPMC6955760

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.