Evidence map›Paper›PMID 31661769›Full record

ArticleInternational journal of molecular sciences2019

Functional Comparison of Human and Zebra Fish FKBP52 Confirms the Importance of the Proline-Rich Loop for Regulation of Steroid Hormone Receptor Activity.

Diondra C Harris, Yenni A Garcia, Cheryl Storer Samaniego, Veronica W Rowlett, Nina R Ortiz, Ashley N Payan, Tatsuya Maehigashi, Marc B Cox

Open access · goldAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Propagation of conformational instability in FK506-binding protein FKBP12.Biochimica et biophysica acta. Proteins and proteomics · 2024
    Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Diondra C HarrisBorder Biomedical Research Center and Department of Biological Sciences, University of Texas at El Paso, El Paso, TX 79968, USA. diondra.harris@gmail.com.
Yenni A GarciaBorder Biomedical Research Center and Department of Biological Sciences, University of Texas at El Paso, El Paso, TX 79968, USA. yagarcia@chem.ucla.edu.
Cheryl Storer SamaniegoBorder Biomedical Research Center and Department of Biological Sciences, University of Texas at El Paso, El Paso, TX 79968, USA. csamaniego@kettering.edu.
Veronica W RowlettBorder Biomedical Research Center and Department of Biological Sciences, University of Texas at El Paso, El Paso, TX 79968, USA. veronicarowlett@gmail.com.
Nina R OrtizBorder Biomedical Research Center and Department of Biological Sciences, University of Texas at El Paso, El Paso, TX 79968, USA. nrortiz@miners.utep.edu.
Ashley N PayanBorder Biomedical Research Center and Department of Biological Sciences, University of Texas at El Paso, El Paso, TX 79968, USA. anpayan@miners.utep.edu.
Tatsuya MaehigashiDepartment of Pediatrics, School of Medicine, Emory University, Atlanta, GA 30322, USA. t.maehigashi@gmail.com.
Marc B CoxBorder Biomedical Research Center and Department of Biological Sciences, University of Texas at El Paso, El Paso, TX 79968, USA. mbcox@utep.edu.ORCID 0000-0001-7854-2676
The University of Texas at El Paso · USEmory University · US

Funding

RISE Scholars Program at UTEPR25GM069621 · NIGMS · UNIVERSITY OF TEXAS EL PASO · PI AGUILERA, RENATO J · 2004 to 2021
$11.2M
Department of Defense (DOD) Prostate Cancer Research Program (PCRP) W81XWH-17-1-0435Dr. Keelung Hong Graduate Research Fellowship N/AFrank B. Cotton Trust Scholarship N/ALizanell and Colbert Coldwell Foundation N/ANational Institutes on Minority Health and Health Disparities (NIMHD) 2G12MD007592RISE Scholars Program at UTEP (NIGMS) R25GM069621-11
6 · The paper itself

Abstract

Previous studies demonstrated that the 52-kDa FK506-binding protein (FKBP52) proline-rich loop is functionally relevant in the regulation of steroid hormone receptor activity. While zebra fish (

Indexed as

AnimalsFibroblastsGain of Function MutationHSP90 Heat-Shock ProteinsHumansMiceMice, KnockoutMolecular Dynamics SimulationProline-Rich Protein DomainsReceptors, AndrogenReceptors, GlucocorticoidSaccharomyces cerevisiaeSignal TransductionTacrolimus Binding ProteinsZebrafish ProteinsHSP90 Heat-Shock ProteinsReceptors, AndrogenReceptors, Glucocorticoidtacrolimus binding protein 4Tacrolimus Binding ProteinsZebrafish Proteinsandrogen receptorcochaperoneDanio rerioFKBP52glucocorticoid receptorheat shock protein 90 (Hsp90)Hsp70progesterone receptorproline-rich loopsteroid hormone receptorzebra fish

Identifiers

PMID31661769
PMCPMC6862696
OpenAlexW2982131253

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.