Evidence map›Paper›PMID 31661752›Full record

ArticleYeungnam University journal of medicine2020

Clinical factors that affect the pregnancy rate in frozen-thawed embryo transfer in the freeze-all policy.

Seo Yoon Hwang, Eun Hye Jeon, Seung Chul Kim, Jong Kil Joo

Abstract read
In one paragraph

Article in Yeungnam University journal of medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Seo Yoon HwangDepartment of Obstetrics and Gynecology, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Korea.
Eun Hye JeonDepartment of Obstetrics and Gynecology, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Korea.
Seung Chul KimDepartment of Obstetrics and Gynecology, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Korea.
Jong Kil JooDepartment of Obstetrics and Gynecology, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Korea.

Funding

Pusan National University Hospital
6 · The paper itself

Abstract

backgroundThis study was conducted to analyze clinical factors that can affect pregnancy rates in normal responders undergoing the freeze-all policy in in vitro fertilization.

methodsWe evaluated 153 embryo transfer cycles in 89 infertile women with normal response to controlled ovarian stimulation (COS). After COS, all embryos were cultured to the blastocyst stage, and good quality blastocysts were vitrified for elective frozen-thawed embryo transfer (FET). Clinical variables associated with COS and the results of COS and culture, including the number of retrieved oocytes, fertilized oocytes, and frozen blastocysts were compared between the pregnant group and the non-pregnant group.

resultsAfter a single cycle of COS for each patient, 52 patients became pregnant while 37 did not. Significant differences were observed in the number of matured oocytes, fertilized oocytes, frozen blastocysts, and transferred embryos. The number of frozen blastocysts in the pregnant group was almost twice that in the non-pregnant group (5.6±3.1 vs. 2.8±1.9, p<0.001). The area under the receiver operating characteristic curve for the 4 frozen blastocysts was 0.801 in the pregnant group.

conclusionIn the freeze-all policy, the number of matured oocytes, number of fertilized oocytes, and number of frozen blastocysts might be predictive factors for pregnancy.

Indexed as

BlastocystEmbryo transferIn vitro fertilizationPregnancy

Identifiers

PMID31661752
PMCPMC6986958

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.