ArticleJornal brasileiro de nefrologia
Fluid and hemodynamic management in hemodialysis patients: challenges and opportunities.
Article in Jornal brasileiro de nefrologia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07459348 (Can Changes in Dialysate Sodium Concentration Improve Blood Pressure and Endothelial Function in Patients Undergoing Chronic Hemodialysis?), which is not on this map. Cited by 48 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Can Changes in Dialysate Sodium Concentration Improve Blood Pressure and Endothelial Function in Patients Undergoing Chronic Hemodialysis?
Who cites it
48 citing papers in PubMed, 103 citations in OpenAlex.
- The central role of habit in fluid management: a longitudinal study in patients on maintenance hemodialysis.BMC nephrology · 2026Article
- Article
- Comparative Efficacy and Safety of Drug-Coated Balloon Angioplasty versus Conventional Balloon Angioplasty for Arteriovenous Access Stenosis in Hemodialysis Patients.International journal of general medicine · 2026Article
- Association of Optimized Nursing Care with Clinical and Patient-Reported Outcomes in Maintenance Hemodialysis Patients: A Retrospective Before-After Study.Patient preference and adherence · 2026Article
- Relationship between hypertension during dialysis and body composition in non-overweight/overweight obese patients.PloS one · 2026Article
- Point-of-Care Ultrasonography in Advanced Nephrology Nursing Practice: Seeing Beyond the Numbers.Diagnostics (Basel, Switzerland) · 2025Review
- Choosing dialysis modality in patients aged 75 and above with end-stage kidney disease: a multicenter cohort study.Scientific reports · 2025Article
- Prediction of ultrafiltration volume in maintenance hemodialysis patients using an artificial neural network model based on body composition information.BMC medical informatics and decision making · 2025Article
- Robotic Nephrectomy in a Patient With a Single Kidney: An Approach Ensuring Safety and Success.Cureus · 2025Article
- Evaluation of seismocardiography in detecting pre-load changes and cardiovascular disease: a comparative study with transthoracic echocardiography.European heart journal. Digital health · 2025Article
- Brain natriuretic peptide and all-cause mortality in patients treated with haemodialysis.BMC nephrology · 2025Observational
- Utility of Central Venous Oxygen Saturation Gradient in Predicting Mortality in Dialysis with Catheter Access.Medical science monitor : international medical journal of experimental and clinical research · 2025Article
- Prognostic Significance of Visit-to-Visit Ultrafiltration Volume Variability in Hemodialysis Patients.Biomedicines · 2025Article
- A Randomized Controlled Clinical Trial of Individualized Patient Education on Hemodialysis Adequacy and Interdialytic Weight Gain.Journal of caring sciences · 2025Article
- Brain surface area and function alterations are correlated with cognition in patients with end-stage renal disease.Quantitative imaging in medicine and surgery · 2025Article
- Self-Care Behaviors in Patients Receiving Hemodialysis: A Systematic Review of Recent Evidence.International journal of preventive medicine · 2025Review
- Association Between Blood Pressure Variation During Dialysis and Cardio-Cerebrovascular Events.Journal of clinical hypertension (Greenwich, Conn.) · 2025Article
- Analysis of risk factors and application of risk management strategies in hemodialysis patients complicated with heart failure.Frontiers in cardiovascular medicine · 2025Article
- Predictors of self-care in kidney transplant patients according to preoperative dialysis: A comparative study.Heliyon · 2024Article
- Associations of Abnormal Fluid Status, Plasma Sodium Disorders, and Low Dialysate Sodium with Mortality in Patients on Hemodialysis.Clinical journal of the American Society of Nephrology : CJASN · 2024Article
Corrections and comments
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Authors and funding
4 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fluid volume and hemodynamic management in hemodialysis patients is an essential component of dialysis adequacy. Restoring salt and water homeostasis in hemodialysis patients has been a permanent quest by nephrologists summarized by the 'dry weight' probing approach. Although this clinical approach has been associated with benefits on cardiovascular outcome, it is now challenged by recent studies showing that intensity or aggressiveness to remove fluid during intermittent dialysis is associated with cardiovascular stress and potential organ damage. A more precise approach is required to improve cardiovascular outcome in this high-risk population. Fluid status assessment and monitoring rely on four components: clinical assessment, non-invasive instrumental tools (e.g., US, bioimpedance, blood volume monitoring), cardiac biomarkers (e.g. natriuretic peptides), and algorithm and sodium modeling to estimate mass transfer. Optimal management of fluid and sodium imbalance in dialysis patients consist in adjusting salt and fluid removal by dialysis (ultrafiltration, dialysate sodium) and by restricting salt intake and fluid gain between dialysis sessions. Modern technology using biosensors and feedback control tools embarked on dialysis machine, with sophisticated analytics will provide direct handling of sodium and water in a more precise and personalized way. It is envisaged in the near future that these tools will support physician decision making with high potential of improving cardiovascular outcome.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.