Evidence map›Paper›PMID 31661056›Full record

ArticleEmerging infectious diseases2020

Tick-Borne Encephalitis Virus, United Kingdom.

Maya Holding, Stuart D Dowall, Jolyon M Medlock, Daniel P Carter, Steven T Pullan, James Lewis, Richard Vipond, Mara S Rocchi, Matthew Baylis, Roger Hewson

Open access · diamondAbstract read
In one paragraph

Article in Emerging infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
8.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 123 citations in OpenAlex.

  1. Article
  2. Babesiosis and Its Significance in Transfusion Medicine from a European Point of View.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2026
    Review
  3. Review
  4. Article
  5. Article
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  7. Identifying hotspots and risk factors for tick-borne encephalitis virus emergence at its range margins to guide interventions, Great Britain.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Tick-borne zoonotic flaviviruses andOne health (Amsterdam, Netherlands) · 2024
    Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Maya Holding
Stuart D Dowall
Jolyon M Medlock
Daniel P Carter
Steven T Pullan
James Lewis
Richard Vipond
Mara S Rocchi
Matthew Baylis
Roger Hewson
Genomics (United Kingdom) · GBMoredun Research Institute · GBHealth Protection Research Unit in Emerging and Zoonotic Infections at University of Liverpool · GBNational Institute for Health Research · GBPublic Health England · GBUniversity of Liverpool · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During February 2018-January 2019, we conducted large-scale surveillance for the presence and prevalence of tick-borne encephalitis virus (TBEV) and louping ill virus (LIV) in sentinel animals and ticks in the United Kingdom. Serum was collected from 1,309 deer culled across England and Scotland. Overall, 4% of samples were ELISA-positive for the TBEV serocomplex. A focus in the Thetford Forest area had the highest proportion (47.7%) of seropositive samples. Ticks collected from culled deer within seropositive regions were tested for viral RNA; 5 of 2,041 ticks tested positive by LIV/TBEV real-time reverse transcription PCR, all from within the Thetford Forest area. From 1 tick, we identified a full-length genomic sequence of TBEV. Thus, using deer as sentinels revealed a potential TBEV focus in the United Kingdom. This detection of TBEV genomic sequence in UK ticks has important public health implications, especially for undiagnosed encephalitis.

Indexed as

Encephalitis Viruses, Tick-BorneAnimalsDeerEncephalitis, Tick-BorneEnzyme-Linked Immunosorbent AssayFemaleHemagglutination Inhibition TestsHumansIxodidaeMalePhylogenyReverse Transcriptase Polymerase Chain ReactionRNA, ViralSentinel SpeciesSequence Analysis, RNAUnited KingdomRNA, Viraldeerflavivirusimmunological surveillanceIxodes ricinuslouping ill virusmeningitis/encephalitissentinel animalsTBEVtick-borne encephalitistick-borne encephalitis virustickborne infectionsticksUnited Kingdomvector-borne infectionsviruseszoonoses

Identifiers

PMID31661056
PMCPMC6924911
OpenAlexW2982371951

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.