Evidence map›Paper›PMID 31661002›Full record

ArticleJournal of cardiothoracic surgery2019

Morbidity and mortality of serious gastrointestinal complications after lung transplantation.

Annette Zevallos-Villegas, Rodrigo Alonso-Moralejo, Félix Cambra, Ana Hermida-Anchuelo, Virginia Pérez-González, Pablo Gámez-García, Javier Sayas-Catalán, Alicia De Pablo-Gafas

Open access · goldAbstract read
In one paragraph

Article in Journal of cardiothoracic surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Medical Complications of Lung Transplantation.Journal of chest surgery · 2022
    Article
  3. Non-pulmonary complications after lung transplantation: part II.Indian journal of thoracic and cardiovascular surgery · 2022
    Review
  4. Recipient Comorbidities for Prediction of Primary Graft Dysfunction, Chronic Allograft Dysfunction and Survival After Lung Transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Annette Zevallos-VillegasDepartment of Respiratory Medecine, Lung Transplant Unit, "12 de Octubre" University Hospital, "i + 12" Research Institute, Avda de Córdoba s/n, 28041, Madrid, Spain. iankazv@yahoo.es.ORCID http://orcid.org/0000-0003-2351-1754
Rodrigo Alonso-MoralejoDepartment of Respiratory Medecine, Lung Transplant Unit, "12 de Octubre" University Hospital, "i + 12" Research Institute, Avda de Córdoba s/n, 28041, Madrid, Spain.
Félix CambraDepartment of General and Digestive Surgery, "12 de Octubre" University Hospital, Madrid, Spain.
Ana Hermida-AnchueloDepartment of Anesthesiology, Lung Transplant Unit, "12 de Octubre" University Hospital, Madrid, Spain.
Virginia Pérez-GonzálezDepartment of Respiratory Medecine, Lung Transplant Unit, "12 de Octubre" University Hospital, "i + 12" Research Institute, Avda de Córdoba s/n, 28041, Madrid, Spain.
Pablo Gámez-GarcíaDepartment of Thoracic Surgery, Lung Transplant Unit, "12 de Octubre" University Hospital, Madrid, Spain.
Javier Sayas-CatalánDepartment of Respiratory Medecine, Lung Transplant Unit, "12 de Octubre" University Hospital, "i + 12" Research Institute, Avda de Córdoba s/n, 28041, Madrid, Spain.
Alicia De Pablo-GafasDepartment of Respiratory Medecine, Lung Transplant Unit, "12 de Octubre" University Hospital, "i + 12" Research Institute, Avda de Córdoba s/n, 28041, Madrid, Spain.
Research Institute Hospital 12 de Octubre · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGastrointestinal complications after lung transplatation are associated with an increased risk of morbidity and mortality. This study aims to describe severe gastrointestinal complications (SGC) after lung transplantation.

methodsWe performed a prospective, observational study that included 136 lung transplant patients during a seven year period in a tertiary care universitary hospital. SGC were defined as any diagnosis related to the gastrointestinal or biliary tract leading to lower survival rates or an invasive therapeutic procedure. Early and late complications were defined as those occurring < 30 days and ≥ 30 days post-transplant. The survival function was calculated through the Kaplan-Meier estimator. Variables were analyzed using univariate and multivariate analysis. Statistical significance was defined as p < 0.05.

resultsThere were 17 (12.5%) SGC in 17 patients. Five were defined as early. Twelve patients (70.6%) required surgical treatment. Mortality was 52.9% (n = 9). Patients with SGC had a lower overall survival rate compared to those who did not (14 vs 28 months, p = 0.0099). The development of arrhythmias in the first 48 h of transplantation was a risk factor for gastrointestinal complications (p = 0.0326).

conclusionsSGC are common after lung transplantation and are associated with a considerable increase in morbidity-mortality. Early recognition is necessary to avoid delays in treatment, since a clear predictor has not been found in order to forecast this relevant comorbidity.

Indexed as

AdultAgedComorbidityFemaleGastrointestinal DiseasesHumansKaplan-Meier EstimateLung DiseasesLung TransplantationMaleMiddle AgedMorbidityMultivariate AnalysisPostoperative ComplicationsProspective StudiesRisk FactorsGastrointestinal complicationsLung transplantationMortalitySurgical complication

Identifiers

PMID31661002
PMCPMC6819340
OpenAlexW2982591210

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.