Evidence map›Paper›PMID 31660963›Full record

ArticleBMC veterinary research2019

Investigation on Brucella infection in farm animals in Saham, Sultanate of Oman with reference to human brucellosis outbreak.

Yasmin ElTahir, Anfal Al-Farsi, Waleed Al-Marzooqi, Alghalya Al-Toobi, Osman M Gaafar, Maryne Jay, Yannick Corde, Shekar Bose, Abeer Al-Hamrashdi, Kaadhia Al-Kharousi and 6 more

Erratum issuedOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC veterinary research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

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  7. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 2 countries.

Yasmin ElTahirDepartment of Animal & Veterinary Sciences, College of Agricultural & Marine Sciences, Sultan Qaboos University, P.O.box 34, 123, Alkhod, Sultanate of Oman. yasmin@squ.edu.om.ORCID 0000-0002-0246-826X
Anfal Al-FarsiDepartment of Animal & Veterinary Sciences, College of Agricultural & Marine Sciences, Sultan Qaboos University, P.O.box 34, 123, Alkhod, Sultanate of Oman.
Waleed Al-MarzooqiDepartment of Animal & Veterinary Sciences, College of Agricultural & Marine Sciences, Sultan Qaboos University, P.O.box 34, 123, Alkhod, Sultanate of Oman.
Alghalya Al-ToobiDepartment of Animal & Veterinary Sciences, College of Agricultural & Marine Sciences, Sultan Qaboos University, P.O.box 34, 123, Alkhod, Sultanate of Oman.
Osman M GaafarDepartment of Animal & Veterinary Sciences, College of Agricultural & Marine Sciences, Sultan Qaboos University, P.O.box 34, 123, Alkhod, Sultanate of Oman.
Maryne JayParis-Est University/Anses, EU/OIE/FAO & National Reference Laboratory for Brucellosis, Animal Health Laboratory, Maisons-Alfort, France.
Yannick CordeParis-Est University/Anses, EU/OIE/FAO & National Reference Laboratory for Brucellosis, Animal Health Laboratory, Maisons-Alfort, France.
Shekar BoseDepartment of Natural Resources Economics, Sultan Qaboos University, P.O.box 34, 123, Alkhod, Sultanate of Oman.
Abeer Al-HamrashdiDepartment of Animal & Veterinary Sciences, College of Agricultural & Marine Sciences, Sultan Qaboos University, P.O.box 34, 123, Alkhod, Sultanate of Oman.
Kaadhia Al-KharousiDepartment of Animal & Veterinary Sciences, College of Agricultural & Marine Sciences, Sultan Qaboos University, P.O.box 34, 123, Alkhod, Sultanate of Oman.
Sunil RajamonyDepartment of Animal & Veterinary Sciences, College of Agricultural & Marine Sciences, Sultan Qaboos University, P.O.box 34, 123, Alkhod, Sultanate of Oman.
Muhammed Nadeem AsiDepartment of Animal & Veterinary Sciences, College of Agricultural & Marine Sciences, Sultan Qaboos University, P.O.box 34, 123, Alkhod, Sultanate of Oman.
Nasseb Al-SaqriDepartment of Animal & Veterinary Sciences, College of Agricultural & Marine Sciences, Sultan Qaboos University, P.O.box 34, 123, Alkhod, Sultanate of Oman.
Rudaina AlBusaidiDepartment of Animal & Veterinary Sciences, College of Agricultural & Marine Sciences, Sultan Qaboos University, P.O.box 34, 123, Alkhod, Sultanate of Oman.
Elshafie I ElshafieDepartment of Animal & Veterinary Sciences, College of Agricultural & Marine Sciences, Sultan Qaboos University, P.O.box 34, 123, Alkhod, Sultanate of Oman.
Eugene H JohnsonDepartment of Animal & Veterinary Sciences, College of Agricultural & Marine Sciences, Sultan Qaboos University, P.O.box 34, 123, Alkhod, Sultanate of Oman.
Sultan Qaboos University · OMDépartement Santé Animale · FR

Funding

Sultan Qaboos University SR/ANVS/01/14
6 · The paper itself

Abstract

backgroundThe objective of this study was to investigate Brucella infection in farm animals in Saham, Oman, with reference to a survey carried out by the Ministry of Agriculture & Fisheries (MAF) for Brucellosis during the period of May to July 2016 in Saham, following an outbreak of human brucellosis. We wanted to apply different serological, bacteriological and molecular tests in a time frame (phase 1, 2 & 3) with reference to the pivotal time of a human brucellosis outbreak to ascertain the status of the disease in Saham area where the MAF survey was conducted. Blood samples were collected from farm animals and sera were screened in parallel for Brucella antibodies using different serological tests.

resultsUsing the RBT test, phase 1 sera showed seropositivity in sheep at 2.6%, (95% CI: 0.5-13.5%), in camel (5.9%, 1.1-27.0%), but not in sera from goats and cattle (0%). Using I-ELISA, seropositivity in goat was 3.1% (0.6-15.8%), with no positive sheep and cattle. Using c-ELISA for camel we found a seropositivity of 5.9% (1.1-27.0%). Furthermore, CFT seropositivity in goats was 21.9% (CI: 11.3-38.9), cattle and sheep sera were negative and camel was 5.9% (1.1-27.0%). In phase 2, the seropositivity in goats was 1.9% (1.4-2.6%), sheep 4.5% (3.5-5.8%), cattle 1.1%, (0.5-2.3%) and camels 18.2% (5.1-47.7%), Phase 3 sera were collected 6 months after the human brucellosis outbreak. With RBT, the seropositivity in goats was 3% (1.0-8.5%), sheep 2% (0.6-7.1%) cattle 1% (0.2-5.5%). With I-ELISA, goats & camels were negative, sheep were 3% (1.0-8.5%) and cattle 1% (0.2-5.5%). Moreover, B. melitensis was isolated from a bronchial lymph node of the RBT and I-ELISA seropositive cow and confirmed by Multiplex PCR and biochemical tests.

conclusionUsing a retrospective study analysis of animal sera and following up after a human brucellosis outbreak, the present study showed a slight decrease in seropositivity of infected animals after the MAF implemented test and slaughter policy. The most interesting finding in this study was the isolation, identification and molecular characterization of Brucella melitensis in a cow (spillover), which is not a preferential host for Brucella melitensis.

Indexed as

Serologic TestsAnimalsAntibodies, BacterialBrucellaBrucellosisDisease OutbreaksHumansLivestockOmanAntibodies, BacterialBrucella melitensisBrucellosisOmanSaham

Identifiers

PMID31660963
PMCPMC6819579
OpenAlexW2982215209

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.