ReviewBMC biology2019
The human gut bacteria Christensenellaceae are widespread, heritable, and associated with health.
Review in BMC biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 468 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
468 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The gut microbiota-obesity axis in the pathogenesis and prognosis of breast cancer.Annals of medicine · 2026Pooled it
- Gut microbial diversity at baseline conditions the clinical, microbiome, and metabolic response to paraprobioticGut microbes · 2026Trial
- Combined ProbioticMolecules (Basel, Switzerland) · 2026Trial
- Trial
- Weight, habitual fibre intake, and microbiome composition predict tolerance to fructan supplementation.International journal of food sciences and nutrition · 2024Trial
- Gut microbiome remodeling and metabolomic profile improves in response to protein pacing with intermittent fasting versus continuous caloric restriction.Nature communications · 2024Trial
- Gut-derived bacterial extracellular vesicles: the microbial dark matter contributing to host inflammation and cardiometabolic disease.Gut microbes · 2026Review
- Dynamic flexibility of the murine gut microbiota during morphine disturbance enables escape from the stable dysbiosis that is associated with addiction-like behavior.Gut microbes · 2026Article
- Distinct trajectories of urbanization shape the human gut microbiome across South Asia.Gut microbes · 2026Article
- Article
- Exercise intensity as a modulator of gut microbiota and host metabolic health in obesity.Gut microbes · 2026Review
- Effects of Expansion Temperature on Fiber Characteristics, Feed Processing Quality, and Growth Performance of Pigs FedAnimals : an open access journal from MDPI · 2026Article
- Article
- The long-lived immune system of centenarians.Nature reviews. Immunology · 2026Review
- A genomic catalog of Earth's bacterial and archaeal symbionts.Nature biotechnology · 2026Article
- Oral iron-induced stunting is associated with increased Christensenella abundance in a piglet model for human infants.European journal of nutrition · 2026Article
- Comparative analysis of meat quality, nutritional composition and gut microbiota in different breeds of meat-type quails.Poultry science · 2026Article
- Dietary Yeast Hydrolysate Alters Serum Metabolic Profiles and Selected Fecal Bacterial Taxa in Lactating Dezhou Jennies.Microorganisms · 2026Article
- Chitosan-Unconjugated Bilirubin Microspheres Alleviate Dysbiosis, Immune Dysregulation, and Intestinal Barrier Damage in Ulcerative Colitis.Biomolecules · 2026Article
- Early Gut Microbiota and Metabolic Profiles of Neonatal Donkey Foals and a Comparative Study with Maternal Communities.Microorganisms · 2026Article
408 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
The Christensenellaceae, a recently described family in the phylum Firmicutes, is emerging as an important player in human health. The relative abundance of Christensenellaceae in the human gut is inversely related to host body mass index (BMI) in different populations and multiple studies, making its relationship with BMI the most robust and reproducible link between the microbial ecology of the human gut and metabolic disease reported to date. The family is also related to a healthy status in a number of other different disease contexts, including obesity and inflammatory bowel disease. In addition, Christensenellaceae is highly heritable across multiple populations, although specific human genes underlying its heritability have so far been elusive. Further research into the microbial ecology and metabolism of these bacteria should reveal mechanistic underpinnings of their host-health associations and enable their development as therapeutics.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.