Trial reportBMC public health2019
An integrated health delivery platform, targeting soil-transmitted helminths (STH) and canine mediated human rabies, results in cost savings and increased breadth of treatment for STH in remote communities in Tanzania.
Trial report in BMC public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03667079 (Integrating Community-directed Interventions to Eliminate Neglected Tropical Diseases Caused by Soil-transmitted Helminth Infections and Rabies in Tanzania), which is not on this map. Cited by 18 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Integrating Community-directed Interventions to Eliminate Neglected Tropical Diseases Caused by Soil-transmitted Helminth Infections and Rabies in Tanzania
Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.
- Evaluating cross-cutting opportunities for dog-mediated rabies control: a scoping review.Frontiers in microbiology · 2025Pooled it
- How can we better integrate the prevention, treatment, control and elimination of neglected tropical diseases with other health interventions? A systematic review.BMJ global health · 2021Pooled it
- A scoping review of One Health interventions 2005-2025: What has been done, are they effective, and what are the best practices?One health outlook · 2026Article
- Multilevel barriers to dog rabies vaccination uptake in Kilosa District, Tanzania.One health outlook · 2026Article
- Economic methods and spatial scales in One Health: Results from a scoping review.One health (Amsterdam, Netherlands) · 2025Review
- Current state and future directions of interventions for neglected tropical diseases.Nature human behaviour · 2025Review
- An implementation science framework to understand low coverage in mass dog rabies vaccination.PLoS neglected tropical diseases · 2025Article
- One Health interventions and challenges under rural African smallholder farmer settings: A scoping review.One health (Amsterdam, Netherlands) · 2025Review
- Cost-Effectiveness of Treatment for Canine Parasites in Remote Indigenous Communities.EcoHealth · 2025Article
- Comparing vaccination coverage and dog population demographics among four pilot dog rabies vaccination strategies in Uganda.Frontiers in veterinary science · 2025Article
- How are large-scale One Health initiatives targeting infectious diseases and antimicrobial resistance evaluated? A scoping review.One health (Amsterdam, Netherlands) · 2022Article
- "Using the same hand": The complex local perceptions of integrated one health based interventions in East Africa.PLoS neglected tropical diseases · 2022Article
- Article
- Comparison of the egg recovery rates and limit of detection for soil-transmitted helminths using the Kato-Katz thick smear, faecal flotation and quantitative real-time PCR in human stool.PLoS neglected tropical diseases · 2021Article
- Human rabies: prospects for elimination.CAB reviews : perspectives in agriculture, veterinary science, nutrition and natural resources · 2021Article
- Rabies vaccination strategies in the Netherlands in 2018: a cost evaluation.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2020Article
- COVID-19 in pastoral contexts in the greater Horn of Africa: Implications and recommendations.Pastoralism : research, policy and practice · 2020Article
- Sharing the Load by One Health: Integrating Canine Rabies Vaccination With Bovine Foot-and-Mouth Vaccination Program and Community Public Health Services in Rural Nilgiris District, Tamil Nadu, India.Indian journal of community medicine : official publication of Indian Association of Preventive & Social MedicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 5 institutions in 3 countries.
Funding
Abstract
backgroundAchieving the Sustainable Development Goal of a 90% reduction in neglected tropical diseases (NTDs) by 2030 requires innovative control strategies. This proof-of-concept study examined the effectiveness of integrating control programs for two NTDs: mass drug administration (MDA) for soil-transmitted helminths in humans and mass dog rabies vaccination (MDRV).
methodsThe study was carried out in 24 Tanzanian villages. The primary goal was to demonstrate the feasibility of integrating community-wide MDA for STH and MDRV for rabies. The objectives were to investigate the popularity, participation and cost and time savings of integrated delivery, and to investigate the reach of the MDA with respect to primary school-aged children and other community members. To implement, we randomly allocated villages for delivery of MDA and MDRV (Arm A), MDA only (Arm B) or MDRV only (Arm C).
resultsCommunity support for the integrated delivery was strong (e.g. 85% of focus group discussions concluded that it would result in people getting "two for one" health treatments). A high proportion of households participated in the integrated Arm A events (81.7% MDA, 80.4% MDRV), and these proportions were similar to those in Arms B and C. These findings suggest that coverage might not be reduced when interventions are integrated. Moreover, in addition to time savings, integrated delivery resulted in a 33% lower cost per deworming dose and a 16% lower cost per rabies vaccination. The median percentage of enrolled primary school children treated by this study was 76%. However, because 37% of the primary school aged children that received deworming treatment were not enrolled in school, we hypothesize that the employed strategy could reach more school-aged children than would be reached through a solely school-based delivery strategy.
conclusionsIntegrated delivery platforms for health interventions can be feasible, popular, cost and time saving. The insights gained could be applicable in areas of sub-Saharan Africa that are remote or underserved by health services. These results indicate the utility of integrated One Health delivery platforms and suggest an important role in the global campaign to reduce the burden of NTDs, especially in hard-to-reach communities.
trial registrationclinicaltrials.gov NCT03667079 , retrospectively registered 11th September 2018.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.