ArticleBMC microbiology2019
Genetic variation of Mycoplasma hyopneumoniae from Brazilian field samples.
Article in BMC microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 11 citations in OpenAlex.
- Article
- Exploring the Genetic Diversity ofMicroorganisms · 2024Article
- Rationalizing the use of common parameters and technological tools to follow up Mycoplasma hyopneumoniae infections in pigs.Porcine health management · 2024Article
- Chimeric proteins of Mycoplasma hyopneumoniae as vaccine and preclinical model for immunological evaluation.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024Article
- Detection and partial molecular characterization of Picobirnavirus in swine from the state of Minas Gerais, Brazil.The Journal of veterinary medical science · 2020Article
- Correction to: Genetic variation of Mycoplasma hyopneumoniae from Brazilian field samples.BMC microbiology · 2019Article
Corrections and comments
- Erratum issued
Authors and funding
11 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPorcine enzootic pneumonia is a worldwide problem in swine production. The infected host demonstrates a respiratory disease whose etiologic agent is Mycoplasma hyopneumoniae (Mhp). A total of 266 lung samples with Mycoplasma-like lesions were collected from two slaughterhouses. We analyzed the genetic profile of Mhp field samples using 16 genes that encode proteins involved in the mechanisms of bacterial pathogenesis and/or the immune responses of the host. Bioinformatic analyses were performed to classify the Mhp field samples based on their similarity according to the presence of the studied genes.
resultsOur results showed variations in the frequency of the 16 studied genes among different Mhp field samples. It was also noted that samples from the same farm were genetically different from each other and samples from different regions could be genetically similar, which is evidence of the presence of different genetic profiles among the Mhp field strains that circulate in Brazilian swine herds.
conclusionThis work demonstrated the genetic diversity of several Mhp field strains based on 16 selected genes related to virulence and/or immune response in Brazil. Our findings demonstrate the difference between Mhp field strains could influence the virulence, and we hypothesize that the most frequent genes in Mhp field strains could possibly be used as vaccine candidates. Based on our results, we suspect that Mhp genetic variability may be associated with the frequency of genes among the field strains and we have demonstrated that some Mhp field samples could not have many important genes described in the literature.
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