Evidence map›Paper›PMID 31660582›Full record

ArticleClinical and experimental immunology2020

Circulating β cell-specific CD8

L Yeo, I Pujol-Autonell, R Baptista, M Eichmann, D Kronenberg-Versteeg, S Heck, G Dolton, A K Sewell, T Härkönen, M-L Mikk and 5 more

Open access · hybridAbstract read
In one paragraph

Article in Clinical and experimental immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Sex as a modifier of genetic risk for type 1 diabetes.Diabetes, obesity & metabolism · 2025
    Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Islet-specific CD8Immunology and cell biology · 2023
    Article
  13. Role of mitochondrial DNA in diabetes Mellitus Type I and Type II.Saudi journal of biological sciences · 2022
    Review
  14. Review
  15. Article
  16. CD8Diabetes · 2021
    Article
  17. The Role of Mitochondrial Mutations and Chronic Inflammation in Diabetes.International journal of molecular sciences · 2021
    Review
  18. Article
  19. Review
  20. A predictive CD8Nature reviews. Endocrinology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 2 countries.

L YeoDepartment of Immunobiology, Faculty of Life Sciences and Medicine, King's College London, London, UK.ORCID 0000-0002-9638-4920
I Pujol-AutonellDepartment of Immunobiology, Faculty of Life Sciences and Medicine, King's College London, London, UK.
R BaptistaNational Institute of Health Research Biomedical Research Centre at Guy's and St Thomas' Hospital and King's College London, London, UK.
M EichmannDepartment of Immunobiology, Faculty of Life Sciences and Medicine, King's College London, London, UK.
D Kronenberg-VersteegDepartment of Immunobiology, Faculty of Life Sciences and Medicine, King's College London, London, UK.
S HeckNational Institute of Health Research Biomedical Research Centre at Guy's and St Thomas' Hospital and King's College London, London, UK.
G DoltonDivision of Infection and Immunity, School of Medicine and Systems Immunity Research Institute, Cardiff University, Cardiff, UK.
A K SewellDivision of Infection and Immunity, School of Medicine and Systems Immunity Research Institute, Cardiff University, Cardiff, UK.
T HärkönenResearch Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
M-L MikkImmunogenetics Laboratory, Institute of Biomedicine, University of Turku, Turku, Finland.
J ToppariDepartment of Paediatrics, University of Turku and Turku University Hospital, Turku, Finland.
R VeijolaDepartment of Paediatrics, PEDEGO Research Unit, Medical Research Centre, Oulu University Hospital and University of Oulu, Oulu, Finland.
M KnipResearch Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
J IlonenImmunogenetics Laboratory, Institute of Biomedicine, University of Turku, Turku, Finland.
M PeakmanDepartment of Immunobiology, Faculty of Life Sciences and Medicine, King's College London, London, UK.
St Thomas' Hospital · GBKing's College London · GBUniversity of Turku · FICardiff University · GBUniversity of Helsinki · FIOulu University Hospital · FI

Funding

Department of HealthWellcome Trust WT100327MA
6 · The paper itself

Abstract

In type 1 diabetes (T1D), autoreactive cytotoxic CD8

Indexed as

AutoimmunityCD8-Positive T-LymphocytesChildChild, PreschoolDiabetes Mellitus, Type 1FemaleHistocompatibility Antigens Class IHLA-A24 AntigenHLA-B AntigensHumansInfantInsulinInsulin-Secreting CellsMaleProtein PrecursorsRisk FactorsHistocompatibility Antigens Class IHLA-A*24:02 antigenHLA-A24 AntigenHLA-B AntigensInsulinpreproinsulinProtein PrecursorsCD8+ T cellsHLA-A*24HLA-B*39type 1 diabetes

Identifiers

PMID31660582
PMCPMC7008222
OpenAlexW2982667622

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.