ArticleDevelopment & reproduction2019
Interleukin-8 (IL-8) Expression in the Olive Flounder (
Article in Development & reproduction, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 27 citations in OpenAlex.
- Effects of Immunostimulants on Physiological Performances, Immune Gene Expression, Liver, and Intestinal Protection AgainstAquaculture nutrition · 2025Article
- Effects of Substituting Fishmeal with Soy Protein Concentrate Supplemented with Essential Amino Acids in the Olive Flounder (Animals : an open access journal from MDPI · 2024Article
- Detection and Localization of IL-8 and CXCR1 in Rainbow Trout Larvae in Response toAnimals : an open access journal from MDPI · 2024Article
- Protective efficiency and immune responses to single and booster doses of formalin-inactivated scale drop disease virus (SDDV) vaccine in Asian seabass (Lates calcarifer).BMC veterinary research · 2024Article
- Identification, Expression and Antimicrobial Functional Analysis of Interleukin-8 (IL-8) in Response toAnimals : an open access journal from MDPI · 2024Article
- Modulation of immune genes in the mucosal-associated lymphoid tissues of cobia by Sarcodia suae extract.Veterinary research communications · 2023Article
- Evidence of the Autophagic Process during the Fish Immune Response of Skeletal Muscle Cells againstAnimals : an open access journal from MDPI · 2023Article
- Molecular characterization of four innate immune genes inFish and shellfish immunology reports · 2022Article
- Isolation, Identification, and Investigation of Pathogenic Bacteria From Common Carp (Frontiers in immunology · 2022Article
- Genome based quantification of VHSV in multiple organs of infected olive flounder (Paralichthys olivaceus) using real-time PCR.Genes & genomics · 2020Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Interleukin-8 (IL-8) is an inflammatory cytokine that plays an important role in the inflammatory response through the activation of neutrophil cells. The expression of IL-8 was investigated in early developmental stages of the olive flounder and in tissues of 8-month-old individuals. The expression of IL-8 increased after the initiation of the immune system rather than at the early stage of development, and high expression was observed in the gills and spleen, the organs associated with immunity and metabolism. In addition, IL-8 expression after infection by viral hemorrhagic septicemia virus significantly increased in the fin, gill, muscles, and spleen. These results suggest that IL-8 is closely related to inflammation and immune regulation in the immune response of the olive flounder and may be used as a basis for studies on the immune systems of other fish.
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