Evidence map›Paper›PMID 31660412›Full record

ArticleOpen forum infectious diseases2019

Ribavirin for Chronic Hepatitis E Virus Infection in Ibrutinib-Exposed Patients.

Caroline Protin, Florence Abravanel, Laurent Alric, Suzanne Tavitian, Lucie Obéric, Jacques Izopet, Guillaume Martin-Blondel, Loic Ysebaert

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Caroline ProtinHematology Department, Institut Universitaire du Cancer de Toulouse-Oncopole, Toulouse, France.
Florence AbravanelLaboratory of Virology, CHU Purpan, Toulouse, France.
Laurent AlricInternal Medicine-Digestive Department CHU Toulouse, UMR 152 IRD Toulouse 3 University, France.
Suzanne TavitianHematology Department, Institut Universitaire du Cancer de Toulouse-Oncopole, Toulouse, France.
Lucie ObéricHematology Department, Institut Universitaire du Cancer de Toulouse-Oncopole, Toulouse, France.
Jacques IzopetLaboratory of Virology, CHU Purpan, Toulouse, France.
Guillaume Martin-BlondelDepartment of Infectious and Tropical Diseases, Toulouse University Hospital, France.
Loic YsebaertHematology Department, Institut Universitaire du Cancer de Toulouse-Oncopole, Toulouse, France.ORCID 0000-0003-4102-7261
Centre National de la Recherche Scientifique · FRInstitut universitaire du cancer de Toulouse Oncopole · FRUniversité Toulouse III - Paul Sabatier · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ibrutinib is an oral first-in-class Bruton's tyrosine kinase inhibitor approved for the therapy of various B-cell lymphoid malignancies. Among ibrutinib-related infections, viral hepatitis are poorly described. We report our single-center experience with 4 cases of chronic hepatitis E virus infection and their management with ribavirin.

Indexed as

hematological malignancieshepatitis E virusibrutinibimmuno-deficiencyribavirin

Identifiers

PMID31660412
PMCPMC6798245
OpenAlexW2965748725

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.