Evidence map›Paper›PMID 31660400›Full record

ArticleOpen forum infectious diseases2019

Syphilis Reactivates Latent Epstein-Barr Virus Reservoir via Toll-Like Receptor 2 and B-Cell Receptor Activation.

Julia R Hirsiger, Philipp S Fuchs, Peter Häusermann, Bojana Müller-Durovic, Thomas Daikeler, Mike Recher, Hans H Hirsch, Luigi Terracciano, Christoph T Berger

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
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  6. Article
  7. Article
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  9. Article
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  12. Article
  13. Herpesviral Latency-Common Themes.Pathogens (Basel, Switzerland) · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Julia R HirsigerTranslational Immunology, Department of Biomedicine, University Hospital Basel, Basel, Switzerland.
Philipp S FuchsClinical Immunology, Medical Outpatient Unit, Department of Internal Medicine, University Hospital Basel, Basel, Switzerland.
Peter HäusermannDepartment of Dermatology, University Hospital Basel, Basel, Switzerland.
Bojana Müller-DurovicImmunobiology Laboratory, Department of Biomedicine, University Hospital Basel, Basel, Switzerland.
Thomas DaikelerRheumatology Clinic, University Hospital Basel, Basel, Switzerland.
Mike RecherImmunodeficiency Clinic and Laboratory, Departments of Internal Medicine and Biomedicine, University Hospital Basel, Basel, Switzerland.
Hans H HirschDivision Infection Diagnostics, Department Biomedicine, University Hospital Basel, Basel, Switzerland.
Luigi TerraccianoInstitute of Pathology, University Hospital Basel, Basel, Switzerland.
Christoph T BergerTranslational Immunology, Department of Biomedicine, University Hospital Basel, Basel, Switzerland.ORCID 0000-0002-1730-8824
University Hospital of Basel · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Latent Epstein-Barr virus (EBV) infection can clinically reactivate in immunosuppressed individuals causing lymphoproliferative disease and rarely hepatitis. In this study, we provide in vivo and in vitro evidence that

Indexed as

EBVreactivationsyphilisTLRTreponema pallidum

Identifiers

PMID31660400
PMCPMC6736073
OpenAlexW2955120216

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.