ArticleOpen forum infectious diseases2019
High Hepatitis E virus (HEV) Positivity Among Domestic Pigs and Risk of HEV Infection of Individuals Occupationally Exposed to Pigs and Pork Meat in Hanoi, Vietnam.
Article in Open forum infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 4 of them syntheses that pooled it.
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Who cites it
26 citing papers in PubMed, 4 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- Systematic review and meta-analysis of hepatitis E seroprevalence in Southeast Asia: a comprehensive assessment of epidemiological patterns.BMC infectious diseases · 2024Pooled it
- Meta-analysis and moderator analysis of the seroprevalence of hepatitis E in South-Eastern Asia.Scientific reports · 2023Pooled it
- Prevalence of hepatitis E virus in China from 1997 to 2022: a systematic review and meta-analysis.Frontiers in public health · 2023Pooled it
- A systematic review of the epidemiology of Hepatitis E virus infection in South - Eastern Asia.Virulence · 2021Pooled it
- Molecular and serological evidence of hepatitis E virus genotype 3 circulation in pigs in Senegal.One health (Amsterdam, Netherlands) · 2026Article
- Epidemiological characteristics in Shanghai and a prognostic nomogram for 90 day adverse outcomes in acute hepatitis E.Hepatology international · 2026Article
- First Detection ofPathogens (Basel, Switzerland) · 2026Article
- Hepatitis E virus exposure and risk factors among ethnic minority populations in Northern Vietnam.PloS one · 2026Article
- High Seroprevalence of Hepatitis E Virus Among Patients With Hepatitis B and Those With Hepatitis of Unknown Etiology in Central Vietnam.Open forum infectious diseases · 2025Article
- Decoding the virome reveals diverse novel viruses in tree shrews (Tupaia belangeri) in Yunnan Province.Virologica Sinica · 2025Article
- Hepatitis E Virus Infection in Vietnamese Pregnant Women with Hepatitis B: Prevalence and Clinical Outcomes.Open forum infectious diseases · 2025Article
- Seroprevalence and risk factors of hantavirus and hepatitis E virus exposure among wildlife farmers in Vietnam.PloS one · 2025Article
- Characterization of zoonotic hepatitis E virus in domestic pigs and wild boar in Vietnam: Implications for public health.One health (Amsterdam, Netherlands) · 2024Article
- A framework for modelling and designing transparency systems: A case of a Vietnamese pork supply chain.Heliyon · 2023Article
- An Update in Knowledge of Pigs as the Source of Zoonotic Pathogens.Animals : an open access journal from MDPI · 2023Review
- High Hepatitis E Virus (HEV) Seroprevalence and No Evidence of HEV Viraemia in Vietnamese Blood Donors.Viruses · 2023Article
- Review
- Molecular and serological investigation of Hepatitis E virus in pigs slaughtered in Northwestern Italy.BMC veterinary research · 2023Article
- Characterization of a Near Full-Length Hepatitis E Virus Genome of Subtype 3c Generated from Naturally Infected South African Backyard Pigs.Pathogens (Basel, Switzerland) · 2022Article
- Hepatitis E virus in pigs and the environment: An updated review of public health concerns.Narra J · 2022Review
Corrections and comments
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Authors and funding
15 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHepatitis E virus (HEV) infection can occur through consumption of undercooked pork meat or exposure to animal feces. Because there are scarce data only in developing countries, we assessed whether pigs might be a potential source of human HEV infections in Vietnam. In addition, we determined anti-HEV seroprevalences in the general population and in individuals professionally exposed to pigs and pork meat.
methodsThe study took place in Hanoi, Vietnam. Liver tissues from domestic pigs (n = 210) and serum samples obtained from individuals occupationally exposed to pigs and pork meat (n = 283) and from unexposed healthy controls (n = 168) were screened for HEV-ribonucleic acid (RNA) by reverse-transcription polymerase chain reaction. The exposed group was divided into pork meat vendors (n = 81), pig farmers (n = 96), and slaughterers (n = 106). Serum samples were subjected to HEV immunoglobulin (Ig)G and IgM enzyme-linked immunosorbent assays. The HEV genotypes were assessed by direct sequencing, followed by phylogenetic analyses.
resultsHepatitis E virus seroprevalence was higher among persons occupationally exposed to pigs/pork meat compared with unexposed individuals (anti-HEV IgM 11% vs 6%,
conclusionsHepatitis E virus circulates in domestic pigs in Hanoi and constitutes a permanent zoonotic disease risk. The high HEV seroprevalence among occupationally exposed individuals indicates an associated risk of HEV infection.
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