Evidence map›Paper›PMID 31660331›Full record

ArticleOpen forum infectious diseases2019

Candidate Predisposition Variants in Kaposi Sarcoma as Detected by Whole-Genome Sequencing.

Sanni J Rinne, Lauri J Sipilä, Päivi Sulo, Emmanuelle Jouanguy, Vivien Béziat, Laurent Abel, Jean-Laurent Casanova, Nima Parvaneh, Kamran Balighi, Emma Guttman-Yassky and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Open forum infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. The biology of SCUBE.Journal of biomedical science · 2023
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 5 countries.

Sanni J RinneApplied Tumor Genomics Research Program and, Helsinki, Finland.
Lauri J SipiläApplied Tumor Genomics Research Program and, Helsinki, Finland.
Päivi SuloApplied Tumor Genomics Research Program and, Helsinki, Finland.
Emmanuelle JouanguyLaboratory of Human Genetics of Infectious Diseases, Necker Branch, Institut National de la Santé et de la Recherche Médicale (INSERM) UMR-1163, Paris, France.
Vivien BéziatLaboratory of Human Genetics of Infectious Diseases, Necker Branch, Institut National de la Santé et de la Recherche Médicale (INSERM) UMR-1163, Paris, France.
Laurent AbelLaboratory of Human Genetics of Infectious Diseases, Necker Branch, Institut National de la Santé et de la Recherche Médicale (INSERM) UMR-1163, Paris, France.
Jean-Laurent CasanovaLaboratory of Human Genetics of Infectious Diseases, Necker Branch, Institut National de la Santé et de la Recherche Médicale (INSERM) UMR-1163, Paris, France.
Nima ParvanehDivision of Allergy and Clinical Immunology, Department of Pediatrics, , Tehran, Iran.
Kamran BalighiDepartment of Dermatology, Razi Hospital, and, Tehran, Iran.
Emma Guttman-YasskyDepartment of Dermatology, Icahn School of Medicine at Mount Sinai, New York, New York.
Ronit SaridThe Mina and Everard Goodman Faculty of Life Sciences & Advanced Materials and Nanotechnology Institute, Bar-Ilan University, Ramat-Gan, Israel.
Lauri A AaltonenApplied Tumor Genomics Research Program and, Helsinki, Finland.
Mervi AavikkoApplied Tumor Genomics Research Program and, Helsinki, Finland.
Finnish Cancer Registry · FIInserm · FRBar-Ilan University · ILHoward Hughes Medical Institute · USIcahn School of Medicine at Mount Sinai · USRockefeller University · USTehran University of Medical Sciences · IRUniversity of Helsinki · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Familial clustering of classic Kaposi sarcoma (CKS) is rare with, approximately 100 families reported to date. We studied 2 consanguineous families, 1 Iranian and 1 Israeli, with multiple cases of adult CKS and without overt underlying immunodeficiency. We performed genome-wide linkage analysis and whole-genome sequencing to discover the putative genetic cause for predisposition. A 9-kb homozygous intronic deletion in

Indexed as

CDHR5classic Kaposi sarcomagenetic linkagegenetic predispositionRP11-259O2.1SCUBE2whole-genome sequencing

Identifiers

PMID31660331
PMCPMC6778425
OpenAlexW2965566763

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.