Evidence map›Paper›PMID 31660307›Full record

ReviewAnnals of translational medicine2019

Intravenous cangrelor as a peri-procedural bridge with applied uses in ischemic events.

Venugopal B Bhattad, Sathvika Gaddam, Margaret A Lassiter, Pooja S Jagadish, Devarshi Ardeshna, Brandon Cave, Rami N Khouzam

Open access · diamondAbstract readReview
In one paragraph

Review in Annals of translational medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.9field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Venugopal B BhattadDepartment of Internal Medicine, Division of Cardiovascular Diseases, East Tennessee State University, Johnson City, TN, USA.
Sathvika GaddamDepartment of Internal Medicine, East Tennessee State University, Johnson City, TN, USA.
Margaret A LassiterCardiovascular Clinical Pharmacy Department, Johnson City Medical Center, Johnson City, TN, USA.
Pooja S JagadishDepartment of Internal Medicine.
Devarshi ArdeshnaCollege of Medicine, University of Tennessee Health Science Center, Memphis, TN, USA.
Brandon CaveDepartment of Pharmacy, Methodist University Hospital, Memphis, TN, USA.
Rami N KhouzamDepartment of Internal Medicine, Division of Cardiovascular Diseases, University of Tennessee Health Science Center, Memphis, TN, USA.
East Tennessee State University · USUniversity of Tennessee Health Science Center · USJohnson City Medical Center · USMethodist University Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cangrelor is a relatively new antiplatelet drug that has been approved for use as an adjunct therapy to percutaneous coronary intervention (PCI) to decrease peri-procedural myocardial infarction (MI), coronary revascularization, and stent thrombosis. Cangrelor is an adenosine triphosphate analogue with a pharmacokinetic mechanism based on a reversible, dose-dependent inhibition adenosine diphosphate (ADP)-induced platelet aggregation. This drug has lately been in the spotlight as a possible bridge therapy for anti-platelet medication prior to cardiac and non-cardiac surgeries. Platelet function is usually restored within sixty minutes of cessation of therapy, thereby decreasing the risk of bleeding while providing adequate pre-procedural coverage to reduce ischemic events. This manuscript reviews the literature on cangrelor and summarizes its role as a peri-procedural bridge.

Indexed as

CangrelorP2Y12percutaneous coronary intervention (PCI)peri-procedural bridge

Identifiers

PMID31660307
PMCPMC6787394
OpenAlexW2968201211

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.