Evidence map›Paper›PMID 31660075›Full record

ReviewTheranostics2019

Advances in refunctionalization of erythrocyte-based nanomedicine for enhancing cancer-targeted drug delivery.

Da Sun, Jia Chen, Yuan Wang, Hao Ji, Renyi Peng, Libo Jin, Wei Wu

Abstract readReview
In one paragraph

Review in Theranostics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed.

  1. Review
  2. Beyond autologousMolecular therapy. Oncology · 2026
    Review
  3. Review
  4. A Chemically InducedVaccines · 2026
    Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Nano Delivery System for Atherosclerosis.Journal of functional biomaterials · 2024
    Review
  13. Review
  14. Article
  15. Review
  16. Review
  17. Review
  18. Fe-HCOF-PEGInternational journal of nanomedicine · 2024
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Da SunInstitute of Life Sciences, Wenzhou University, Wenzhou, 325035, China.
Jia ChenSichuan Provincial Center for Mental Health, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Chengdu, 610072, China.
Yuan WangChongqing Business Vocational College, Chongqing, 401331, China.
Hao JiInstitute of Life Sciences, Wenzhou University, Wenzhou, 325035, China.
Renyi PengInstitute of Life Sciences, Wenzhou University, Wenzhou, 325035, China.
Libo JinInstitute of Life Sciences, Wenzhou University, Wenzhou, 325035, China.
Wei WuInstitute of Life Sciences, Wenzhou University, Wenzhou, 325035, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer remains a daunting and cureless disease, which is responsible for one-sixth of human deaths worldwide. These mortality rates have been expected to rise in the future due to the side effects of conventional treatments (chemotherapy, radiotherapy, and surgery), which can be addressed by applying nanomedicine. In order to escape from biological barriers, such nanomedicine should be mimicked and designed to be stealthy while navigating in the bloodstream. To achieve this, scientists take advantage of erythrocytes (red blood cells; RBCs) as drug carriers and develop RBC membrane (RBCm) coating nanotechnology. Thanks to the significant advances in nanoengineering, various facile surface functionalization methods can be applied to arm RBCm with not only targeting moieties, but also imaging agents, therapeutic agents, and nanoparticles, which are useful for theranostic nanomedicine. This review focuses on refunctionalization of erythrocyte-based nanomedicine for enhancing cancer-targeted drug delivery.

Indexed as

AnimalsAntineoplastic AgentsCell MembraneDrug CarriersDrug Delivery SystemsErythrocytesHumansNanomedicineNeoplasmsAntineoplastic AgentsDrug Carrierscancererythrocytesnanomedicinerefunctionalization

Identifiers

PMID31660075
PMCPMC6815958

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.