Evidence map›Paper›PMID 31660032›Full record

ArticleWorld journal of gastroenterology2019

Gender differences in vascular reactivity of mesenteric arterioles in portal hypertensive and non-portal hypertensive rats.

Bin Zhang, Lin-Hua Ji, Cheng-Gang Zhang, Gang Zhao, Zhi-Yong Wu

Open access · hybridAbstract read
In one paragraph

Article in World journal of gastroenterology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Hepatic immune regulation and sex disparities.Nature reviews. Gastroenterology & hepatology · 2024
    Review
  3. Blood Pressure Variability Early After Liver Transplantation Predicts Long-Term Mortality.Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Bin ZhangDepartment of Gastrointestinal Surgery, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China.
Lin-Hua JiDepartment of Gastrointestinal Surgery, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China.
Cheng-Gang ZhangDepartment of Gastrointestinal Surgery, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China.
Gang ZhaoDepartment of Gastrointestinal Surgery, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China. zhaogang@renji.com.
Zhi-Yong WuDepartment of Gastrointestinal Surgery, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China.
Shanghai Jiao Tong University · CNRenji Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPortal hypertension (PHT) is primarily caused by an increase in resistance to portal outflow and secondarily by an increase in splanchnic blood flow. Vascular hyporeactivity both in systemic circulation and in the mesenteric artery plays a role in the hyperdynamic circulatory syndrome.

aimTo explore gender differences and the role of endogenous sex hormones in PHT and vascular reactivity of mesenteric arterioles in rats.

methodsCirrhosis and PHT were established by subcutaneous injection of carbon tetrachloride (CCl

resultsNo significant difference in portal pressure was observed between integral and castrated male PHT rats (15.2 ± 2.1 mmHg

conclusionClear gender differences were observed in mesenteric vascular reactivity in CCl

Indexed as

AnimalsArteriolesCarbon TetrachlorideFemaleGonadal Steroid HormonesHumansHypertension, PortalLiver Cirrhosis, ExperimentalMaleMesenteric ArteriesPortal PressureRatsRats, Sprague-DawleySex FactorsSplanchnic CirculationVascular ResistanceCarbon TetrachlorideGonadal Steroid HormonesVasoconstrictor AgentsEstrogenGenderLiver cirrhosisPortal hypertensionVascular reactivity

Identifiers

PMID31660032
PMCPMC6815798
OpenAlexW2980394129

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.