Evidence map›Paper›PMID 31660022›Full record

ArticleJournal of orthopaedics

Hypoalbuminemia remains an independent predictor of complications following total joint arthroplasty.

George W Fryhofer, Matthew Sloan, Neil P Sheth

Open access · greenAbstract read
In one paragraph

Article in Journal of orthopaedics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 39 citations in OpenAlex.

  1. Pooled it
  2. [Prehabilitation before total knee arthroplasty].Orthopadie (Heidelberg, Germany) · 2024
    Pooled it
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  7. Hypoalbuminemia increases risks for complications after surgical repair of nonunions and malunions.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025
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  13. Why malnutrition in orthopaedic elective patient is still an issue? A recent review of the literature.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

George W FryhoferUniversity of Pennsylvania, Department of Orthopaedic Surgery, 3737 Market Street, Philadelphia, PA, 19104, USA.
Matthew SloanUniversity of Pennsylvania, Department of Orthopaedic Surgery, 3737 Market Street, Philadelphia, PA, 19104, USA.
Neil P ShethUniversity of Pennsylvania, Department of Orthopaedic Surgery, 800 Spruce Street, 8th Floor Preston Building, Philadelphia, PA, 19107, USA.
University of Pennsylvania · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionHypoalbuminemia (<3.5 mg/dL) is an accepted marker of malnutrition, but it was unknown if low albumin remained an independent predictor of post-operative complications following primary total hip (THA) and knee (TKA) arthroplasty.

methodsThe National Surgical Quality Improvement Program (NSQIP) database was queried for patients undergoing primary THA and TKA. Propensity score-matched analysis was used to control for co-morbid conditions.

resultsPatients with low albumin demonstrated greater odds of death (by 2-21x), morbidity (by 25-51%), re-admission (by 45-54%), and increased length of stay.

conclusionLow albumin remains an independent predictor of adverse outcomes following primary total joint arthroplasty.

Indexed as

AlbuminMalnutritionOutcomesPrimary hip arthroplastyPrimary knee arthroplasty

Identifiers

PMID31660022
PMCPMC6806651
OpenAlexW2943828346

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.