Evidence map›Paper›PMID 31659655›Full record

Trial reportJournal of general internal medicine2020

Primary Care Providers' Acceptance of Pharmacists' Recommendations to Support Optimal Medication Management for Patients with Diabetic Kidney Disease.

Leah L Zullig, Shelley A Jazowski, Clemontina A Davenport, Clarissa J Diamantidis, Megan M Oakes, Sejal Patel, Jivan Moaddeb, Hayden B Bosworth

Registry-linked trialOpen access · bronzeAbstract readObservational StudyRandomized Controlled Trial
In one paragraph

Trial report in Journal of general internal medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01829256 (Simultaneous Risk Factor Control Using Telehealth to SlOw Progression of Diabetic Kidney Disease), which is not on this map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01829256 nacompletednot on this map

Simultaneous Risk Factor Control Using Telehealth to SlOw Progression of Diabetic Kidney Disease (STOP-DKD)

TypeinterventionalSponsorDuke UniversityRan2014 to 2018Enrolled285ConditionsDiabetes, Hypertension, Diabetic Kidney DiseaseArmsPharmacist telehealth intervention
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Education programmes for people with chronic kidney disease and diabetes.The Cochrane database of systematic reviews · 2024
    Pooled it
  2. Article
  3. Lessons learned from two randomized controlled trials: CITIES and STOP-DKD.Contemporary clinical trials communications · 2020
    Article
  4. Article
  5. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Leah L ZulligCenter of Innovation to Accelerate Discovery and Practice Transformation (ADAPT), Durham Veterans Affairs Health Care System, Durham, NC, USA.
Shelley A JazowskiDepartment of Population Health Sciences, Duke University, Durham, NC, USA.
Clemontina A DavenportDepartment of Biostatistics and Bioinformatics, Duke University, Durham, NC, USA.
Clarissa J DiamantidisDepartment of Population Health Sciences, Duke University, Durham, NC, USA.
Megan M OakesDepartment of Population Health Sciences, Duke University, Durham, NC, USA.
Sejal PatelDivision of General Internal Medicine, Duke University, Durham, NC, USA.
Jivan MoaddebDivision of General Internal Medicine, Duke University, Durham, NC, USA.
Hayden B BosworthCenter of Innovation to Accelerate Discovery and Practice Transformation (ADAPT), Durham Veterans Affairs Health Care System, Durham, NC, USA. boswo001@duke.edu.ORCID 0000-0001-6188-9825
Duke University · USUniversity of North Carolina at Chapel Hill · US

Funding

Support for QA/QC for Prior Approval ProcessUL1TR002553 · NCATS · DUKE UNIVERSITY · PI LI, JENNIFER S, MCNAMARA, JAMES O. · 2018 to 2023
$58.5M
Multi-factorial Intervention to Slow Progression of Diabetic Kidney DiseaseR01DK093938 · NIDDK · DUKE UNIVERSITY · PI BOSWORTH, HAYDEN B, DIAMANTIDIS, CLARISSA JONAS · 2013 to 2017
$3.4M
Is there a digital divide in Chronic Kidney Disease (CKD)?K23DK099385 · NIDDK · DUKE UNIVERSITY · PI DIAMANTIDIS, CLARISSA JONAS · 2014 to 2017
$678k
HSR&D Senior Research Career Scientist AwardIK6HX003161 · VA · DURHAM VA MEDICAL CENTER · PI Hayden B Bosworth · 2020 to 2026
–
HSRD VA IK6 HX003161NCATS NIH HHS UL1 TR002553NIDDK NIH HHS K23 DK099385NIDDK NIH HHS R01 DK093938
6 · The paper itself

Abstract

backgroundPatients with diabetic kidney disease (DKD) often struggle with blood pressure control. In team-based models of care, pharmacists and primary care providers (PCPs) play important roles in supporting patients' blood pressure management.

objectiveTo describe whether PCPs' acceptance of pharmacists' recommendations impacts systolic blood pressure (SBP) at 36 months.

designAn observational analysis of a subset of participants randomized to the intervention arm of the Simultaneous risk factor control using Telehealth to slOw Progression of Diabetic Kidney Disease (STOP-DKD) study.

participantsSTOP-DKD participants for whom (1) the pharmacist made at least one recommendation to the PCP; (2) there were available data regarding the PCP's corresponding action; and (3) there were SBP measurements at baseline and 36 months.

interventionParticipants received monthly telephone calls with a pharmacist addressing health behaviors and medication management. Pharmacists made medication-related recommendations to PCPs. MAIN MEASURES: We fit an unadjusted generalized linear mixed model to assess the association between the number of pharmacists' recommendations for DKD and blood pressure management and PCPs' acceptance of such recommendations. We used a linear regression model to evaluate the association between PCP acceptance and SBP at 36 months, adjusted for baseline SBP. KEY

resultsPharmacists made 176 treatment recommendations (among 59 participants), of which 107 (61%) were accepted by PCPs. SBP significantly declined by an average of 10.5 mmHg (p < 0.01) among 47 of 59 participants who had valid measurements at baseline and 36 months. There was a significant association between the number of pharmacist recommendations and the odds of PCP acceptance (OR 1.19; 95%CI 1.00, 1.42; p < 0.05), but no association between the number of accepted recommendations and SBP.

conclusionsPharmacists provided actionable medication-related recommendations. We identified a significant decline in SBP at 36 months, but this reduction was not associated with recommendation acceptance.

trial registrationNCT01829256.

Indexed as

Diabetes MellitusDiabetic NephropathiesHealth PersonnelHumansMedication Therapy ManagementPharmacistsPrimary Health Careblood pressure controldiabetic kidney diseasemedication managementteam-based primary care

Identifiers

PMID31659655
PMCPMC6957634
OpenAlexW2981878039

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.