ArticleDocumenta ophthalmologica. Advances in ophthalmology2020
Increase in electroretinogram rod-driven peak frequency of oscillatory potentials and dark-adapted responses in a cohort of myopia patients.
Article in Documenta ophthalmologica. Advances in ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- The Complications of Myopia: A Review and Meta-Analysis.Investigative ophthalmology & visual science · 2020Pooled it
- Measuring electroretinograms in tree shrews with a portable electrophysiology device.Documenta ophthalmologica. Advances in ophthalmology · 2026Article
- The oscillatory response of the electroretinogram and neuronal adaptation.Acta ophthalmologica · 2026Review
- S-Cone Retinal Pathway Dysfunction in Myopia.Investigative ophthalmology & visual science · 2026Article
- Mechanisms Underlying Myopia Progression from Visual Signaling to Metabolic Remodeling in Retina.JMA journal · 2025Review
- Measuring differences in the ERG in myopia using the RETeval device with skin electrodes.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2025Article
- Early Alterations in Inner-Retina Neural and Glial Saturated Responses in Lens-Induced Myopia.Translational vision science & technology · 2024Article
- Paediatric norms for photopic electroretinogram testing based on a large cohort of Chinese preschool children.BMJ open ophthalmology · 2024Article
- RBP3-Retinopathy-Inherited High Myopia and Retinal Dystrophy: Genetic Characterization, Natural History, and Deep Phenotyping.American journal of ophthalmology · 2024Article
- Enhancing Electroretinogram Classification with Multi-Wavelet Analysis and Visual Transformer.Sensors (Basel, Switzerland) · 2023Article
- ON and OFF receptive field processing in the presence of optical scattering.Biomedical optics express · 2023Article
- Applications of Genomics and Transcriptomics in Precision Medicine for Myopia Control or Prevention.Biomolecules · 2023Review
- Flash Electroretinography as a Measure of Retinal Function in Myopia and Hyperopia: A Systematic Review.Vision (Basel, Switzerland) · 2023Review
- The Development of Electroretinographic Oscillatory Potentials in Healthy Young Children.Journal of clinical medicine · 2022Article
- Electroretinogram responses in myopia: a review.Documenta ophthalmologica. Advances in ophthalmology · 2022Review
- Posterior scleral reinforcement for the treatment of myopic traction maculopathy.BMC ophthalmology · 2022Article
- Electrical responses from human retinal cone pathways associate with a common genetic polymorphism implicated in myopia.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Increase in b-wave amplitude after light stimulation of the blind spot is positively correlated with the axial length of myopic individuals.Scientific reports · 2022Article
- High-Resolution Image Analysis Reveals a Decrease in Lens Thickness and Cone Density in a Cohort of Young Myopic Patients.Frontiers in medicine · 2021Article
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo study whether rod- and cone-driven electroretinogram (ERG) responses are altered in myopia patients.
methodsDark- and light-adapted ERGs were recorded from 57 myopic eyes of 32 patients aged 22-30 and 19 emmetropic eyes of 10 age-matched normal subjects. The myopic eyes were divided into 3 groups according to spherical equivalent (SE) of manifest refraction: 18 low myopia eyes (≤ - 3.00 diopter (D), 23 moderate myopia eyes (- 3.25 to - 6.00 D), and 16 high myopia eyes (> - 6.25 D). The amplitudes of the dark- and light-adapted ERG a- and b-waves, as well as the frequency spectra of the cone-driven and rod-driven oscillatory potentials (OPs), were analyzed by fast Fourier transform. The peak frequency, implicit time, and total power of the OPs were determined. The axial length was measured with an IOL Master. The ERG parameters including those of the cone- and rod-driven OPs were compared among three groups.
resultsThe amplitudes of the a-wave and b-wave of the dark-adapted ERGs were increased with refractive power (P < 0.05). Interestingly, the average peak frequency of the rod-driven OPs showed a significant positive correlation with refractive power (P < 0.001): 123.41 ± 9.13 Hz in emmetropic controls, 129.12 ± 10.28 Hz in low myopia, 133.90 ± 9.13 Hz in moderate myopia, and 139.51 ± 5.78 Hz in high myopia. However, the parameters of the light-adapted ERGs and the cone-driven OPs in myopic eyes were within normal ranges.
conclusionWe found significant positive correlation between the peak frequency of rod-driven OPs, as well as the amplitudes of rod-driven ERG a- and b-waves, and the refractive power. The results suggest that the rod system function was changing during the progress of myopia, while the cone system function appeared unaffected. The peak frequency of OPs appeared as a novel ERG parameter for myopia, a common ocular condition.
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