Evidence map›Paper›PMID 31659573›Full record

ArticleFunctional & integrative genomics2020

A transcriptomic study of selenium against liver injury induced by beta-cypermethrin in mice by RNA-seq.

Kan He, Qingyang Tang, Mengting Gong, Silin Yang, Xianping Chen, Huiqiu Zhu, Dahai Liu, Bei Huang

Abstract read
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In one paragraph

Article in Functional & integrative genomics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kan HeCenter for Stem Cell and Translational Medicine, School of Life Sciences, Anhui University, 111 Jiulong Road, Hefei City, 230601, Anhui Province, China.
Qingyang TangCenter for Stem Cell and Translational Medicine, School of Life Sciences, Anhui University, 111 Jiulong Road, Hefei City, 230601, Anhui Province, China.
Mengting GongCenter for Stem Cell and Translational Medicine, School of Life Sciences, Anhui University, 111 Jiulong Road, Hefei City, 230601, Anhui Province, China.
Silin YangAnhui Province Huaxin Biological Medical Co. Ltd., Jieshou, 236501, Anhui, China.
Xianping ChenAnhui No. 2 Provincial People's Hospital, Heifei, 230041, Anhui, China.
Huiqiu ZhuAnhui Province Huaxin Biological Medical Co. Ltd., Jieshou, 236501, Anhui, China.
Dahai LiuSchool of Stomatology and Medicine, Foshan University, Foshan, 528000, Guangdong, China.
Bei HuangCenter for Stem Cell and Translational Medicine, School of Life Sciences, Anhui University, 111 Jiulong Road, Hefei City, 230601, Anhui Province, China. beihuang@163.com.

Funding

Natural Science Foundation Project of Anhui Province 1508085QC63 and 1908085MC87the Natural Science Foundation of China 81570376 and 81870307the Promoting Project for Team Construction of Anhui Province, China Y05201374the Scientific Research Foundation and Academic & Technology Leaders Introduction Project, and 211 Project of Anhui University 10117700023the Tackle key Problem Project in Science and Technology in Anhui Province, China 1501041177
6 · The paper itself

Abstract

Evidence from biochemical liver function index and histopathology analysis suggested that selenium could effectively repair the liver injury caused by beta-cypermethrin (β-CYP). However, the molecular mechanism of selenium against liver injury induced by β-CYP remains unclear. In the present study, dynamic changes in gene expression profiles before and after the treatment of Na

Indexed as

TranscriptomeAnimalsChemical and Drug Induced Liver InjuryCytochrome P-450 Enzyme SystemInsecticidesJanus KinasesLiverMicePyrethrinsSeleniumSTAT Transcription FactorscypermethrinCytochrome P-450 Enzyme SystemInsecticidesJanus KinasesPyrethrinsSeleniumSTAT Transcription FactorsGenesLiver injuryPathwaysRNA sequencingSelenium

Identifiers

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.