ArticleSurgical endoscopy2020
Primary and metastatic melanoma of the GI tract: clinical presentation, endoscopic findings, and patient outcomes.
Article in Surgical endoscopy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 24 citations in OpenAlex.
- The Development and Validation of a Nomogram for Predicting Cancer-Specific Survival and a Risk Stratification System for Patients with Primary Gastrointestinal Melanoma.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2023Trial
- Article
- An Unusual Case of Upper Digestive Bleeding-Metastatic Amelanotic Melanoma: Case Report and Literature Review.Life (Basel, Switzerland) · 2026Article
- Primary melanoma of the gastrointestinal tract.World journal of gastroenterology · 2026Review
- Acral melanoma presenting with multiple intussusceptions: a case report and literature review.Frontiers in oncology · 2026Article
- From the Skin to Small Bowel: Metastatic Melanoma as a Hidden Source of Gastrointestinal Bleeding.Cureus · 2025Article
- Prognostic models based on lymph node density for primary gastrointestinal melanoma: a SEER population-based analysis.BMJ open · 2023Observational
- Malignant melanoma of gastrointestinal tract onAmerican journal of nuclear medicine and molecular imaging · 2023Article
- BRAF, NRAS, KIT, TERT, GNAQ/GNA11 Mutation Profile and Histomorphological Analysis of Anorectal Melanomas: A Clinicopathologic Study.Turk patoloji dergisi · 2023Article
- Metastatic melanoma presenting with dyspepsia: a case report.The Journal of international medical research · 2022Article
- Early diagnosis of primary melanoma of caecum. Case report and review of the literature.Acta bio-medica : Atenei Parmensis · 2021Review
- Epidemiology and survival outcomes of primary gastrointestinal melanoma: a SEER-based population study.International journal of clinical oncology · 2020Article
- Melanoma of unknown primary presenting as intestinal obstruction: a diagnostic challenge.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologieArticle
- Diffuse Metastatic Melanoma in the GI Lumen Following Immune Checkpoint Inhibitor Colitis Treatment.Case reports in gastroenterologyArticle
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimsMelanoma incidence has increased worldwide with a concurrent rise in both primary and metastatic melanomas of the gastrointestinal tract. MATERIALS AND
methodsThis retrospective single-center case series includes patients with histopathology-confirmed primary or metastatic melanoma of the GI tract between 1998 and 2018.
resultsThirty-four patients were identified for inclusion, of whom 7 were primary and 27 were metastatic cases of gastrointestinal melanoma. For both primary and metastatic cases, the majority of patients presented with frank or occult GI bleeding (57.1% and 70.4%). Primary and metastatic lesions were predominantly diagnosed endoscopically (100% and 63.0%), with 71.4% of primary lesions found at the anorectal junction and 51.9% of metastatic lesions in the small bowel. Endoscopically diagnosed lesions were either polypoid (50%) or a luminal mass (37.5%) in the majority of cases. Common features included: amelanotic (83%), ulcerated (50%), and friable (33.3%). All primary patients were treated with surgical excision or resection. Of the metastatic patients, 56% were resected. The median interval between initial primary and gastrointestinal metastases was 65 months (ranging from 1 month to 24 years). At the time of data analysis, 85.7% of primary and 29.6% of metastatic patients remained alive.
conclusionsThe majority of patients in this series were diagnosed endoscopically while investigating a source of gastrointestinal blood loss. Heightened clinical suspicion and recognition of the endoscopic features of gastrointestinal melanoma during evaluation of GI symptoms in a patient with a personal history of primary melanoma are advised.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.