Evidence map›Paper›PMID 31659307›Full record

ArticleNature biomedical engineering2020

Functionalized helical fibre bundles of carbon nanotubes as electrochemical sensors for long-term in vivo monitoring of multiple disease biomarkers.

Liyuan Wang, Songlin Xie, Zhiyuan Wang, Fei Liu, Yifan Yang, Chengqiang Tang, Xiaoying Wu, Peng Liu, Yongjing Li, Hexige Saiyin and 5 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature biomedical engineering, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 93 papers.

0numbers the graph read from it
0cells of the map it votes in
93citing papers in PubMed
12.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

93 citing papers in PubMed, 361 citations in OpenAlex.

  1. Design, Construction, and Application of Implantable Fiber Biosensors.Advanced materials (Deerfield Beach, Fla.) · 2026
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  13. Review
  14. Beyond fiber electronics.National science review · 2025
    Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Stimuli-responsive hybrid materials for 4DMaterials today. Bio · 2025
    Review

33 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Liyuan Wang *State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science and Laboratory of Advanced Materials, Fudan University, Shanghai, China.
Songlin Xie *State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science and Laboratory of Advanced Materials, Fudan University, Shanghai, China.
Zhiyuan Wang *Vision Research Laboratory, School of Life Sciences, State Key Laboratory of Medical Neurobiology, Collaborative Innovation Centre for Brain Science, Fudan University, Shanghai, China.
Fei LiuDepartment of Aeronautics and Astronautics, Fudan University, Shanghai, China.
Yifan YangDepartment of Aeronautics and Astronautics, Fudan University, Shanghai, China.
Chengqiang TangState Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science and Laboratory of Advanced Materials, Fudan University, Shanghai, China.
Xiaoying WuState Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science and Laboratory of Advanced Materials, Fudan University, Shanghai, China.
Peng LiuState Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science and Laboratory of Advanced Materials, Fudan University, Shanghai, China.
Yongjing LiState Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science and Laboratory of Advanced Materials, Fudan University, Shanghai, China.
Hexige SaiyinVision Research Laboratory, School of Life Sciences, State Key Laboratory of Medical Neurobiology, Collaborative Innovation Centre for Brain Science, Fudan University, Shanghai, China.ORCID http://orcid.org/0000-0003-2993-6817
Shuang ZhengState Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science and Laboratory of Advanced Materials, Fudan University, Shanghai, China.
Xuemei SunState Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science and Laboratory of Advanced Materials, Fudan University, Shanghai, China. sunxm@fudan.edu.cn.ORCID http://orcid.org/0000-0002-2583-8593
Fan XuDepartment of Aeronautics and Astronautics, Fudan University, Shanghai, China. fanxu@fudan.edu.cn.ORCID http://orcid.org/0000-0003-3910-5398
Hongbo YuVision Research Laboratory, School of Life Sciences, State Key Laboratory of Medical Neurobiology, Collaborative Innovation Centre for Brain Science, Fudan University, Shanghai, China. hongboyu@fudan.edu.cn.ORCID http://orcid.org/0000-0002-1641-2152
Huisheng PengState Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science and Laboratory of Advanced Materials, Fudan University, Shanghai, China. penghs@fudan.edu.cn.ORCID http://orcid.org/0000-0002-2142-2945
Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mechanical mismatches between implanted electronics and biological tissues can lead to inaccurate readings and long-term tissue damage. Here, we show that functionalized multi-walled carbon nanotubes twisted into helical fibre bundles that mimic the hierarchical structure of muscle can monitor multiple disease biomarkers in vivo. The flexible fibre bundles are injectable, have a low bending stiffness and display ultralow stress under compression. As proof-of-concept evidence of the sensing capabilities of these fibre bundles, we show that the fibre bundles enable the spatially resolved and real-time monitoring of H

Indexed as

Nanotubes, CarbonAnimalsBiocompatible MaterialsBiomarkersBiomarkers, TumorBiosensing TechniquesCatsDiabetes Mellitus, Type 1Electrochemical TechniquesFemaleHydrogen PeroxideMaleMiceMice, Inbred BALB CMice, NudeMonitoring, PhysiologicBiocompatible MaterialsBiomarkersBiomarkers, TumorHydrogen PeroxideNanotubes, Carbon

Identifiers

PMID31659307
OpenAlexW2982051194

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.