Evidence map›Paper›PMID 31659144›Full record

ArticleAging2019

Adipose tissue-derived omentin-1 attenuates arterial calcification via AMPK/Akt signaling pathway.

Feng Xu, Fu-Xing-Zi Li, Xiao Lin, Jia-Yu Zhong, Feng Wu, Su-Kang Shan, Chang-Ming Tan, Ling-Qing Yuan, Xiao-Bo Liao

Open access · greenAbstract read
In one paragraph

Article in Aging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.

  1. Pooled it
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  3. The role of omentin-1 in female reproduction: a critical review.The Journal of reproduction and development · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Feng XuDepartment of Endocrinology and Metabolism, Hunan Provincial Key Laboratory of Metabolic Bone Diseases, National Clinical Research Center for Metabolic Diseases, The Second Xiang-Ya Hospital, Central South University, Changsha 410011, Hunan, People's Republic of China.
Fu-Xing-Zi LiDepartment of Endocrinology and Metabolism, Hunan Provincial Key Laboratory of Metabolic Bone Diseases, National Clinical Research Center for Metabolic Diseases, The Second Xiang-Ya Hospital, Central South University, Changsha 410011, Hunan, People's Republic of China.
Xiao LinDepartment of Geriatrics, The Second Xiang-Ya Hospital, Central South University, Changsha 410011, People's Republic of China.
Jia-Yu ZhongDepartment of Geriatrics, The Second Xiang-Ya Hospital, Central South University, Changsha 410011, People's Republic of China.
Feng WuDepartment of Pathology, The Second Xiang-Ya Hospital, Central South University, Changsha 410011, People's Republic of China.
Su-Kang ShanDepartment of Endocrinology and Metabolism, Hunan Provincial Key Laboratory of Metabolic Bone Diseases, National Clinical Research Center for Metabolic Diseases, The Second Xiang-Ya Hospital, Central South University, Changsha 410011, Hunan, People's Republic of China.
Chang-Ming TanDepartment of Cardiovascular Surgery, The Second Xiang-Ya Hospital, Central South University, Changsha 410011, People's Republic of China.
Ling-Qing YuanDepartment of Endocrinology and Metabolism, Hunan Provincial Key Laboratory of Metabolic Bone Diseases, National Clinical Research Center for Metabolic Diseases, The Second Xiang-Ya Hospital, Central South University, Changsha 410011, Hunan, People's Republic of China.
Xiao-Bo LiaoDepartment of Cardiovascular Surgery, The Second Xiang-Ya Hospital, Central South University, Changsha 410011, People's Republic of China.
Central South University · CNHunan Provincial People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adipose tissue-derived adipokines mediate various kind of crosstalk between adipose tissue and other organs and thus regulate metabolism balance, inflammation state as well as disease progression. In particular, omentin-1, a newly found adipokine, has been reported to exhibit anti-calcification effects

Indexed as

Adipose TissueAMP-Activated Protein Kinase KinasesAnimalsCalcinosisCells, CulturedCytokinesGPI-Linked ProteinsHumansLectinsMaleMiceMice, Inbred C57BLMice, KnockoutMuscle, Smooth, VascularMyocytes, Smooth MuscleOsteocalcinAMP-Activated Protein Kinase KinasesCytokinesGPI-Linked ProteinsItln1 protein, mouseLectinsOsteocalcinPhosphorus, DietaryProtein KinasesProto-Oncogene Proteins c-aktAktAMP-activated protein kinasearterial calcificationomentin-1smooth muscle differentiation

Identifiers

PMID31659144
PMCPMC6834406
OpenAlexW2981869803

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.