Evidence map›Paper›PMID 31658966›Full record

ArticleAntimicrobial agents and chemotherapy2019

Efficacy of Humanized Cefiderocol Exposure Is Unaltered by Host Iron Overload in the Thigh Infection Model.

James M Kidd, Kamilia Abdelraouf, David P Nicolau

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Iron serum levels and iron homeostasis parameters in patients with nosocomial pneumonia treated with cefiderocol: post hoc analysis of the APEKS-NP study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2022
    Trial
  2. Iron Dysregulation in Cardiovascular Diseases.Reviews in cardiovascular medicine · 2024
    Review
  3. Article
  4. Review
  5. Article
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  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

James M KiddCenter for Anti-Infective Research and Development, Hartford Hospital, Hartford, Connecticut, USA.
Kamilia AbdelraoufCenter for Anti-Infective Research and Development, Hartford Hospital, Hartford, Connecticut, USA.
David P NicolauCenter for Anti-Infective Research and Development, Hartford Hospital, Hartford, Connecticut, USA david.nicolau@hhchealth.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cefiderocol is a siderophore-cephalosporin conjugate with greater

Indexed as

Acinetobacter baumanniiAnimalsAnti-Bacterial AgentsCefiderocolCephalosporinsDrug Resistance, Multiple, BacterialFemaleGram-Negative BacteriaHumansIronIron OverloadMeropenemMiceMicrobial Sensitivity TestsPseudomonas aeruginosaSiderophoresAnti-Bacterial AgentsCefiderocolCephalosporinsIronMeropenemSiderophoresanimal modelscephalosporinGram-negative bacteriairon regulationsiderophoressoft-tissue infection

Identifiers

PMID31658966
PMCPMC7187581

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.