Evidence map›Paper›PMID 31658834›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2019

Glycocalyx breakdown is increased in African children with cerebral and uncomplicated falciparum malaria.

Tsin W Yeo, Peggy A Bush, Youwei Chen, Sarah P Young, Haoyue Zhang, David S Millington, Donald L Granger, Esther D Mwaikambo, Nicholas M Anstey, J Brice Weinberg

Open access · greenAbstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 22 citations in OpenAlex.

  1. Elevated urinary glycosaminoglycans inJournal of medical microbiology · 2026
    Article
  2. Febrile temperature enhancesbioRxiv : the preprint server for biology · 2025
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Degradation of endothelial glycocalyx in Tanzanian children with falciparum malaria.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2021
    Article
  13. Review
  14. Article
  15. Review
  16. Review
  17. Article
  18. Infection and immunity · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 4 countries.

Tsin W YeoLee Kong Chian School of Medicine, Nanyang Technological University, Singapore.
Peggy A BushDuke University-Veterans Affairs (VA) Medical Center, Durham, North Carolina, USA.
Youwei ChenDuke University-Veterans Affairs (VA) Medical Center, Durham, North Carolina, USA.
Sarah P YoungDuke University-Veterans Affairs (VA) Medical Center, Durham, North Carolina, USA.
Haoyue ZhangDuke University-Veterans Affairs (VA) Medical Center, Durham, North Carolina, USA.
David S MillingtonDuke University-Veterans Affairs (VA) Medical Center, Durham, North Carolina, USA.
Donald L GrangerUniversity of Utah-VA Medical Center, Salt Lake City, Utah, USA.
Esther D MwaikamboHubert Kairuki Memorial University, Dar es Salaam, Tanzania.
Nicholas M AnsteyMenzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia.
J Brice WeinbergDuke University-Veterans Affairs (VA) Medical Center, Durham, North Carolina, USA.
Durham VA Medical Center · USDuke University · USHubert Kairuki Memorial University · TZMenzies School of Health Research · AUTan Tock Seng Hospital · SGUniversity of Utah · US

Funding

NITRIC OXIDE AND SEVERE MALARIAR01AI041764 · NIAID · DUKE UNIVERSITY · PI WEINBERG, JOE BRICE · 1997 to 2012
$6.3M
Nitric Oxide and Microvascular Dysfunction in Severe MalariaR01HL130763 · NHLBI · DUKE UNIVERSITY · PI WEINBERG, JOE BRICE · 2015 to 2018
$1.5M
NHLBI NIH HHS R01 HL130763NIAID NIH HHS R01 AI041764
6 · The paper itself

Abstract

Cerebral malaria (CM) from

Indexed as

BiomarkersChildChild, PreschoolFemaleGlycocalyxGlycosaminoglycansHumansInfantMalaria, CerebralMalaria, FalciparumMaleMethylene BlueParasitemiaTanzaniaBiomarkersdimethylmethylene blueGlycosaminoglycansMethylene Bluecerebral malariaendothelial glycocalyxnitric oxidePlasmodium falciparum

Identifiers

PMID31658834
PMCPMC6894053
OpenAlexW2982486958

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.