Evidence map›Paper›PMID 31658697›Full record

ReviewNutrients2019

Curcumin, Hormesis and the Nervous System.

Maria Concetta Scuto, Cesare Mancuso, Barbara Tomasello, Maria Laura Ontario, Andrea Cavallaro, Francesco Frasca, Luigi Maiolino, Angela Trovato Salinaro, Edward J Calabrese, Vittorio Calabrese

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 4 pooled it
5.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 4 syntheses or guidelines pooled it, 151 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Nutritional Mushroom Treatment in Meniere's Disease withInternational journal of molecular sciences · 2019
    Trial
  6. Curcumin Between Pleiotropic Potential and Translational Constraints.International journal of molecular sciences · 2026
    Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Unlocking the Potential ofMolecules (Basel, Switzerland) · 2025
    Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Role of oxidative stress-induced ferroptosis in cancer therapy.Journal of cellular and molecular medicine · 2024
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Maria Concetta ScutoDepartment of Biomedical and Biotechnological Sciences, University of Catania, Torre Biologica, Via Santa Sofia, 97-95125 Catania, Italy. mary-amir@hotmail.it.ORCID 0000-0003-1019-5158
Cesare MancusoFondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Roma, Italy. cesare.mancuso@unicatt.it.
Barbara TomaselloDepartment of Biomedical and Biotechnological Sciences, University of Catania, Torre Biologica, Via Santa Sofia, 97-95125 Catania, Italy. btomase@unict.it.ORCID 0000-0001-6049-942X
Maria Laura OntarioDepartment of Biomedical and Biotechnological Sciences, University of Catania, Torre Biologica, Via Santa Sofia, 97-95125 Catania, Italy. marialaura.ontario@ontariosrl.it.
Andrea CavallaroDepartment of Biomedical and Biotechnological Sciences, University of Catania, Torre Biologica, Via Santa Sofia, 97-95125 Catania, Italy. andreacavallaro@tiscali.it.ORCID 0000-0002-0311-5191
Francesco FrascaDepartment of Clinical and experimental Medicine, Division of Endocrinology, University of Catania, 95125 Catania, Italy. f.frasca@unict.it.
Luigi MaiolinoDepartment of Medical and Surgery Sciences, University of Catania, 95125 Catania, Italy. maiolino@policlinico.unict.it.
Angela Trovato SalinaroDepartment of Biomedical and Biotechnological Sciences, University of Catania, Torre Biologica, Via Santa Sofia, 97-95125 Catania, Italy. trovato@unict.it.
Edward J CalabreseDepartment of Environmental Health Sciences, School of Public Health and Health Science, University of Massachusetts, Amherst, MA 01003, USA. edwardc@schoolph.umass.edu.
Vittorio CalabreseDepartment of Biomedical and Biotechnological Sciences, University of Catania, Torre Biologica, Via Santa Sofia, 97-95125 Catania, Italy. calabres@unict.it.ORCID 0000-0002-0478-985X
University of Catania · ITUniversità Cattolica del Sacro Cuore · ITUniversity of Massachusetts Amherst · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Curcumin is a polyphenol compound extracted from the rhizome of

Indexed as

CurcuminHormesisAnimalsAntioxidantsHumansMiceNervous SystemNeurodegenerative DiseasesRatsAntioxidantsCurcuminantioxidantsheme oxygenasehormesisvitagenes

Identifiers

PMID31658697
PMCPMC6835324
OpenAlexW2979830091

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.