Evidence map›Paper›PMID 31658374›Full record

ArticleCancer2020

"My doctor says the cancer is worse, but I believe in miracles"-When religious belief in miracles diminishes the impact of news of cancer progression on change in prognostic understanding.

Login S George, Tracy A Balboni, Paul K Maciejewski, Andrew S Epstein, Holly G Prigerson

Abstract readMulticenter Study
In one paragraph

Article in Cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  17. For the Love of Alma, Black Hopes Matter.Palliative medicine reports · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Login S GeorgeDepartment of Psychiatry and Behavioral Sciences, Memorial Sloan Kettering Cancer Center, New York, New York.ORCID 0000-0001-6270-7755
Tracy A BalboniRadiation Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
Paul K MaciejewskiDepartment of Medicine, Weill Cornell Medicine, New York, New York.
Andrew S EpsteinDepartment of Psychiatry and Behavioral Sciences, Memorial Sloan Kettering Cancer Center, New York, New York.ORCID 0000-0003-1808-3070
Holly G PrigersonDepartment of Medicine, Weill Cornell Medicine, New York, New York.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Disparities in COVID Disease Severity and Outcomes in New York CityUL1TR002384 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI JULIANNE L IMPERATO-MCGINLEY · 2017 to 2026
$86.2M
Psychosocial Approaches to Better Understanding & End-Stage Cancer Care (PROTECT)R35CA197730 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI Holly Gwen Prigerson · 2015 to 2026
$11.2M
Psychosocial Palliative & Community Research in CancerT32CA009461 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI JENNIFER L HAY, Jamie S. Ostroff · 1985 to 2026
$10.1M
Quality of Death: Ethnic and Psychosocial InfluencesR01CA106370 · NCI · YALE UNIVERSITY · PI PRIGERSON, HOLLY GWEN · 2004 to 2015
$4.1M
The Weill Cornell Medicine Research Training Program in Behavioral GeriatricsT32AG049666 · NIA · WEILL MEDICAL COLL OF CORNELL UNIV · PI SARA J CZAJA, Manney Carrington Reid · 2016 to 2026
$3.2M
Impact of a Novel Cancer Communication Intervention on Caregiver BereavementR01CA168387 · NCI · UNIVERSITY OF ROCHESTER · PI DUBERSTEIN, PAUL R, PRIGERSON, HOLLY GWEN · 2013 to 2017
$2.6M
Latino vs. Non-Latino Disparities in Advance Care Planning & End-of-Life CareR01MD007652 · NIMHD · WEILL MEDICAL COLL OF CORNELL UNIV · PI MACIEJEWSKI, PAUL K, PRIGERSON, HOLLY GWEN · 2014 to 2018
$1.9M
Psychiatric Disorder in Dying Patients &Their SurvivorsR01MH063892 · NIMH · YALE UNIVERSITY · PI JACOBS, SELBY C · 2002 to 2005
$1.9M
An Investigation of the Clinical Utility of a Prolonged Grief Disorder DiagnosisR21MH095378 · NIMH · SLOAN-KETTERING INST CAN RESEARCH · PI LICHTENTHAL, WENDY G., PRIGERSON, HOLLY GWEN · 2013 to 2014
$504k
Communicating the Gist of Prognosis: Giving Information Simply and Transparently ("GIST") in Advanced CancerR21NR018693 · NINR · WEILL MEDICAL COLL OF CORNELL UNIV · PI EPSTEIN, ANDREW, PRIGERSON, HOLLY GWEN · 2019 to 2020
$488k
Enhancing & Mobilizing the POtential for Wellness & Emotional Resilience (EMPOWER) in Caregivers of ICU Cancer PatientsR21CA218313 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI LICHTENTHAL, WENDY G., PRIGERSON, HOLLY GWEN · 2017 to 2018
$422k
NCATS NIH HHS UL1 TR002384NCI NIH HHS P30 CA008748NCI NIH HHS R01 CA106370NCI NIH HHS R01 CA168387NCI NIH HHS R21 CA218313NCI NIH HHS R35 CA197730NCI NIH HHS T32 CA009461NIA NIH HHS T32 AG049666NIMHD NIH HHS R01 MD007652NIMH NIH HHS R01 MH063892NIMH NIH HHS R21 MH095378NINR NIH HHS R21 NR018693
6 · The paper itself

Abstract

backgroundNews of cancer progression is critical to setting accurate prognostic understanding, which guides patients' treatment decision making. This study examines whether religious belief in miracles modifies the effect of receiving news of cancer progression on change in prognostic understanding.

methodsIn a multisite, prospective cohort study, 158 patients with advanced cancer, whom oncologists expected to die within 6 months, were assessed before and after the visit at which scan results were discussed. Before the visit, religious belief in miracles was assessed; after the visit, patients indicated what scan results they had received (cancer was worse vs cancer was stable, better, or other). Before and after the visit, prognostic understanding was assessed, and a change score was computed.

resultsApproximately 78% of the participants (n = 123) reported at least some belief in miracles, with almost half (n = 73) endorsing the strongest possible belief. A significant interaction effect emerged between receiving news of cancer progression and belief in miracles in predicting change in prognostic understanding (b = -0.18, P = .04). Receiving news of cancer progression was associated with improvement in the accuracy of prognostic understanding among patients with weak belief in miracles (b = 0.67, P = .007); however, among patients with moderate to strong belief in miracles, news of cancer progression was unrelated to change in prognostic understanding (b = 0.08, P = .64).

conclusionsReligious belief in miracles was highly prevalent and diminished the impact of receiving news of cancer progression on prognostic understanding. Assessing patients' beliefs in miracles may help to optimize the effectiveness of "bad news" scan result discussions.

Indexed as

ReligionReligion and PsychologyAgedCohort StudiesDisease ProgressionFemaleHumansMaleMiddle AgedNeoplasmsPhysician-Patient RelationsPhysiciansPrognosisTerminal CareTerminally Illcommunicationcomprehensionlife expectancyprognosisspirituality

Identifiers

PMID31658374
PMCPMC6992494

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.