ArticleEuropean journal of rheumatology2019
QT variability index in patients with systemic sclerosis.
Article in European journal of rheumatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.
- Repolarization in systemic sclerosis: a meta-analysis.Clinical rheumatology · 2022Pooled it
- QTc is Prolonged in Patients with SSc and Associates with Skin Score.Mediterranean journal of rheumatology · 2023Article
- Short-Term Beat-to-Beat QT Variability Appears Influenced More Strongly by Recording Quality Than by Beat-to-Beat RR Variability.Frontiers in physiology · 2022Article
- Heart Rate Influence on the QT Variability Risk Factors.Diagnostics (Basel, Switzerland) · 2020Article
- Electrocardiographic markers for the prediction of ventricular arrhythmias in patients with systemic sclerosis.Rheumatology (Oxford, England) · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveSystemic sclerosis (SSc) may affect the heart with microvascular dysfunction and lead to an early cardiac death, but the association between certain repolarization indexes and SSc heart disease remains controversial. Our goal was to evaluate a previously unstudied marker of repolarization dynamics, i.e., QT variability, in patients with SSc and to assess its prognostic implications.
methodsA total of 17 patients with SSc and 21 healthy controls were included into this prospective study. Electrocardiograms were conducted under strict standards. The QT variability index (QTVI), normalized QT variability (QTVN), and power spectral analysis of QT dynamics, considered as markers of ventricular arrhythmias in a number of other disorders, were determined using designated computer software.
resultsThere was no significant difference in demographic and cardiac important clinical parameters between the groups. Also, the mean QTVI, QTVN, and power spectral analysis parameters were comparable between the patients with SSc and control subjects. At baseline, the QTVI values of 1 patient with SSc, who experienced ventricular arrhythmia prior to inclusion in the study, were considerably higher compared to other patients with SSc. None of the remaining patients with SSc or the control subjects developed arrhythmia during the follow-up of 8 years.
conclusionHigher than normal QTVI may be found in the minority of patients with SSc. The prognostic significance of this finding is unknown, but it may entail an increased risk of ventricular arrhythmias. Therefore, the value of QTVI as a tool for arrhythmia risk stratification in SSc merits further research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.