Evidence map›Paper›PMID 31657600›Full record

ArticleJournal of abnormal psychology2020

Extreme-groups designs in studies of dimensional phenomena: Advantages, caveats, and recommendations.

Joscelyn E Fisher, Anika Guha, Wendy Heller, Gregory A Miller

Abstract read
In one paragraph

Article in Journal of abnormal psychology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Smartphone Addiction Modulates Object-Based Attention.Behavioral sciences (Basel, Switzerland) · 2026
    Article
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  13. Psychiatric neuroimaging designs for individualised, cohort, and population studies.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024
    Review
  14. Article
  15. Article
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  18. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Joscelyn E FisherDepartment of Psychiatry.ORCID 0000-0002-7682-7528
Anika GuhaDepartment of Psychology.ORCID 0000-0002-4576-5037
Wendy HellerDepartment of Psychology.ORCID 0000-0002-6854-558X
Gregory A MillerDepartment of Psychology.

Funding

Proj 5: Early Development (224-250)P50MH079485 · NIMH · UNIVERSITY OF COLORADO · PI BANICH, MARIE T · 2008 to 2012
$8.7M
Enhancing Cognitive Training Through Exercise Following a First Schizophrenia EpisodeR01MH110544 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI NUECHTERLEIN, KEITH H · 2016 to 2022
$7.3M
MECHANISMS OF ATTENTIONAL BIAS IN PSYCHOPATHOLOGYR01MH061358 · NIMH · UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN · PI HELLER, WENDY · 2000 to 2009
$2.6M
TRAINING IN COGNITIVE PSYCHOPHYSIOLOGYT32MH019554 · NIMH · UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN · PI HELLER, WENDY · 1992 to 2012
$2.3M
Neurocognitive Mechanisms: Appetitive &Aversive EmotionR21DA014111 · NIDA · UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN · PI MILLER, GREGORY ALLEN · 2001 to 2003
$549k
Semantic processing in schizophrenia: Symptoms &memoryF31MH068123 · NIMH · UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN · PI FISHER, JOSCELYN ELIZABETH · 2003 to 2005
$100k
NIDA NIH HHS R21 DA014111NIMH NIH HHS F31 MH068123NIMH NIH HHS P50 MH079485NIMH NIH HHS R01 MH061358NIMH NIH HHS R01 MH110544NIMH NIH HHS T32 MH019554
6 · The paper itself

Abstract

Extreme-groups designs (EGDs) are common in psychopathology research, often using diagnostic category as an independent variable. Continuous-variable analysis strategies drawing from a general linear model framework can be applied to such designs. The growing emphasis on dimensional examinations of psychological constructs, encouraged by the National Institute of Mental Health Research Domain Criteria framework, encourages continuous-variable analytic strategies. However, the interpretative implications of applying these strategies to various types of populations and sample score distributions, including those used in EGDs, are not always recognized. Appropriateness and utility of EGDs depend in part on whether the goal is to determine whether a relationship exists between 2 variables or to determine its strength. Whereas the literature investigating EGDs has emphasized symmetrical thresholds for defining extreme groups (e.g., bottom 10% vs. top 10%), psychopathologists often employ asymmetric thresholds (e.g., above a diagnostic threshold vs. a broader range of scores in a healthy comparison group). The present article selectively reviews literature on EGDs and extends it with simulations of symmetric and asymmetric selection criteria. Results indicate that including a wide range of scores in EGDs substantially mitigates problems (e.g., inflation of effect size) that arise when using statistical methods classically employed for continuous variables. (PsycINFO Database Record (c) 2019 APA, all rights reserved).

Indexed as

Mental DisordersResearch DesignHumansLongitudinal StudiesUnited States

Identifiers

PMID31657600
PMCPMC6928394

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.