Evidence map›Paper›PMID 31657247›Full record

ArticleAmerican journal of physiology. Renal physiology2019

Impact of angiotensin II-mediated stimulation of sodium transporters in the nephron assessed by computational modeling.

Aurélie Edwards, Alicia A McDonough

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Renal physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Impact ofMicroorganisms · 2021
    Review
  10. Local and downstream actions of proximal tubule angiotensin II signaling on NaAmerican journal of physiology. Renal physiology · 2021
    Article
  11. Vascular control of kidney epithelial transporters.American journal of physiology. Renal physiology · 2021
    Article
  12. Review
  13. Role of Rho in Salt-Sensitive Hypertension.International journal of molecular sciences · 2021
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Aurélie EdwardsDepartment of Biomedical Engineering, Boston University, Boston, Massachusetts.
Alicia A McDonoughDepartment of Physiology and Neuroscience, Keck School of Medicine of University of Southern California, Los Angeles, California.ORCID 0000-0002-0459-469X
Boston University · USUniversity of Southern California · US

Funding

Sodium transporter regulation during hypertensionR01DK083785 · NIDDK · UNIVERSITY OF SOUTHERN CALIFORNIA · PI AURELIE EDWARDS, Alicia A. McDonough · 2011 to 2026
$5.8M
NIDDK NIH HHS R01 DK083785
6 · The paper itself

Abstract

Angiotensin II (ANG II) raises blood pressure partly by stimulating tubular Na

Indexed as

Angiotensin IIAnimalsBlood PressureComputer SimulationCreatinineEpithelial Sodium ChannelsKidney MedullaKidney Tubules, ProximalLithiumMaleMembrane Transport ProteinsNatriuresisNephronsPotassiumRatsSodiumAngiotensin IICreatinineEpithelial Sodium ChannelsLithiumMembrane Transport ProteinsPotassiumSlc12a1 protein, ratSlc9a3 protein, ratSodiumSodium-Hydrogen Exchanger 3Solute Carrier Family 12, Member 1hypertensionkidneymathematical modelpressure natriuresis

Identifiers

PMID31657247
PMCPMC6962509
OpenAlexW2981757606

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.