ArticleInternational journal of health policy and management2019
Problems and Promises of Health Technologies: The Role of Early Health Economic Modeling.
Article in International journal of health policy and management, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
55 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Economic Evaluations of Magnetic Resonance Image-Guided Radiotherapy (MRIgRT): A Systematic Review.International journal of environmental research and public health · 2022Pooled it
- An Information-Driven Approach for the Early Health Technology Sustainability Assessment and the Frugal Design of the Internet of Medical Things: Exploratory Study of Wearable Activity Monitoring Devices.JMIR mHealth and uHealth · 2026Article
- Establishing multiple cost-effectiveness thresholds in Oman: a stakeholder-driven approach.Health economics review · 2026Review
- Cost-utility of focused ultrasound compared to radiotherapy for Dutch patients with uncomplicated non-spinal bone metastases.The European journal of health economics : HEPAC : health economics in prevention and care · 2026Article
- Introduction of early health technology assessment for innovators, clinicians, and funders.npj health systems · 2026Review
- Prediction of Relapse Using Digital Technology in People in Recovery From Substance Use Disorders: Early Economic Evaluation With a Case Study of the Subreal App.JMIR formative research · 2026Article
- Assessing technologies in dementia care: A conceptual health-economic model.Journal of Alzheimer's disease : JAD · 2026Article
- Evaluating dementia risk prediction in mild cognitive impairment: an early health technology assessment of the AI-Mind tool.GeroScience · 2026Article
- Early health technology assessment of a primary care tool for the diagnosis and management of headaches in Alberta, Canada.International journal of technology assessment in health care · 2026Article
- Manufacturing cost analysis and exploratory economic evaluation of natural killer cell immunotherapy for paediatric solid tumors.Clinical & translational immunology · 2026Article
- From crisis to recovery: Exploring the demand surge for mental health services in Alberta, Canada-A document-based policy analysis with an illustrative supply-demand simulation (2023-2024).PLOS mental health · 2026Article
- Article
- Recommendations for the use of early cost-effectiveness analysis to inform the health technology development process with an application to cutaneous squamous cell carcinoma.International journal of technology assessment in health care · 2025Article
- Early budget impact analysis of magnetic balloon technology for facilitating the completion of difficult colonoscopies.Cost effectiveness and resource allocation : C/E · 2025Article
- Health Technology Assessment in the Early Phases of Development of Medical Devices: A Catalyst for Sustainable Growth and Innovation.Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine · 2025Article
- Innovative Approaches to Improve the Success of Pituitary Surgery in Cushing's Disease: A Cost-Effectiveness Perspective.Clinical endocrinology · 2025Article
- On the potential value of eHTA: a commentary on "Defining Early Health Technology Assessment: Building Consensus Using Delphi Technique".International journal of technology assessment in health care · 2025Article
- Applying early health technology assessment (e-HTA) to inform investment in novel health technologies in the US.International journal of technology assessment in health care · 2025Article
- Predicting response to immunotherapy in lung cancer: an early HTA of predictive tests.International journal of technology assessment in health care · 2025Article
- Supporting translation with early health technology assessment: from definition to action.International journal of technology assessment in health care · 2025Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo assess whether early health economic modeling helps to distinguish those healthcare innovations that are potentially cost-effective from those that are not potentially cost-effective. We will also study what information is retrieved from the health economic models to inform further development, research and implementation decisions.
methodsWe performed secondary analyses on an existing database of 32 health economic modeling assessments of 30 innovations, performed by our group. First, we explored whether the assessments could distinguish innovations with potential cost-effectiveness from innovations without potential cost-effectiveness. Second, we explored which recommendations were made regarding development, implementation and further research of the innovation.
resultsOf the 30 innovations, 1 (3%) was an idea that was not yet being developed and 14 (47%) were under development. Eight (27%) innovations had finished development, and another 7 (23%) innovations were on the market. Although all assessments showed that the innovation had the potential to become cost-effective, due to improved patient outcomes, cost savings or both, differences were found in the magnitude of the potential benefits, and the likelihood of reaching this potential. The assessments informed how the innovation could be further developed or positioned to maximize its cost-effectiveness, and informed further research.
conclusionThe early health economic assessments provided insight in the potential cost-effectiveness of an innovation in its intended context, and the associated uncertainty. None of the assessments resulted in a firm 'no-go' recommendation, but recommendations could be provided on further research and development in order to maximize value for money.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.