Evidence map›Paper›PMID 31657120›Full record

ArticleCancer medicine2019

Competing-risks model for predicting the prognosis of penile cancer based on the SEER database.

Jin Yang, Zhenyu Pan, Yujing He, Fanfan Zhao, Xiaojie Feng, Qingqing Liu, Jun Lyu

Abstract read
In one paragraph

Article in Cancer medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jin YangClinical Research Center, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Zhenyu PanClinical Research Center, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Yujing HeDepartment of Thoracic Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Fanfan ZhaoClinical Research Center, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Xiaojie FengClinical Research Center, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Qingqing LiuClinical Research Center, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Jun LyuClinical Research Center, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.ORCID 0000-0002-2237-8771

Funding

National Social Science Foundation of China 16BGL183Research Fund of Health Bureau of Xi'an QFO1330
6 · The paper itself

Abstract

objectivesThis study performed a competing-risks analysis using data from the SEER database on penile cancer patients with the aim of identifying more accurate prognostic factors.

methodsData on patients with penile cancer were extracted from the SEER database. A univariate analysis used the cumulative incidence function and Gray's test, while multivariate analysis was performed using the Fine-Gray model. Cumulative hazards were compared with a competing-risks model constructed using Kaplan-Meier estimation.

resultsThe multivariate Fine-Gray analysis indicated that being black (HR = 1.51, 95%CI: 1.10-2.07, P = .01), AJCC stage II (HR = 1.94, 95%CI: 1.36-2.77, P < .001), AJCC stage III (HR = 1.98, 95%CI: 1.34-2.91, P < .001), tumor size > 5 cm (HR = 2.23, 95%CI: 1.33-3.72, P < .05), and TNM stages N1 (HR = 2.49, 95%CI: 1.71-3.61, P < .001), N2 (HR = 3.25, 95%CI: 2.18-4.84, P < .001), N3 (HR = 5.05, 95%CI: 2.69-9.50, P < .001), and M1 (HR = 2.21, 95%CI: 1.28-3.84, P < .05) were statistically significant. The results obtained using multivariate Cox regression were different, while Kaplan-Meier curve analysis led to an overestimation of the cumulative risk of the patient.

conclusionsThis study established a competing-risks analysis model for the first time based on the SEER database for the risk assessment of penile cancer patients. The results may help clinicians to better understand penile cancer and provide these patients with more appropriate support.

Indexed as

Models, TheoreticalAgedAged, 80 and overCombined Modality TherapyDisease SusceptibilityFemaleHumansIncidenceMaleMiddle AgedNeoplasm StagingPenile NeoplasmsPrognosisProportional Hazards ModelsRisk AssessmentRisk Factorscompeting-risks modelfine-garypenile cancerprognostic factorsSEER database

Identifiers

PMID31657120
PMCPMC6912058

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