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Institutional Experience of Treatment and Outcomes for Cutaneous Periauricular Squamous Cell Carcinoma.
Article in OTO open. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 14 citations in OpenAlex.
- Article
- Bilateral neglected facial invasive squamous cell carcinoma in an 89-year-old man, complete excision and primary reconstruction by cervicofacial flap, case report and review of current reconstruction approaches.International journal of surgery case reports · 2025Article
- Role of the otologist/neurotologist in managing auricular and periauricular cutaneous malignancies: A 10-year otologic oncology experience.Laryngoscope investigative otolaryngology · 2023Article
- Gene expression profiling for metastatic risk in head and neck cutaneous squamous cell carcinoma.Laryngoscope investigative otolaryngology · 2022Article
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Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
Abstract
objectivesTo report our institutional experience, management, and outcomes of cutaneous periauricular squamous cell carcinoma (SCC). STUDY
designRetrospective chart review.
settingTertiary academic center. SUBJECTS: Patients undergoing treatment of cutaneous periauricular SCC from 2000 to 2016.
resultsA total of 112 patients had a median follow-up of 24.5 months, a mean ± SD age of 75.7 ± 10.6 years, and a strong male predominance (93.8%). Site distribution shows 87 (77.7%) auricular, 26 (23.2%) preauricular, and 10 (8.8%) postauricular lesions. Of auricular lesions, tumors involved the tragus (n = 3, 3.4%), helix/antihelix (n = 47, 54.0%), conchal bowl (n = 31, 35.6%), external auditory canal (n = 18, 16.1%), and lobule (n = 3, 3.4%). Most patients presented at stage I (52.7%) versus stages II (28.6%), III (6.3%), and IV (12.5%). Patients were largely treated surgically with primary tumor resection ranging from wide local excision to lateral temporal bone resection (± parotidectomy and neck dissection), with 17.0% and 5.4% receiving adjuvant radiation and chemoradiation, respectively. Metastatic spread was seen to the parotid (25.9%) and neck (26.8%), with most common cervical spread to level II. Overall survival, disease-specific survival, and disease-free survival at 3 years were 62%, 89%, and 56%, respectively. Nodal disease was associated with worse disease-specific survival (
conclusionAmong cutaneous SCC, periauricular subsites pose treatment challenges related to surrounding anatomy and represent a unique tumor population. The reported propensity toward recurrence and patterns of metastasis may better guide treatment of aggressive tumors to include regional nodal dissection.
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