Evidence map›Paper›PMID 31656932›Full record

ArticleACS omega2019

Decapping Scavenger Enzyme Activity toward N2-Substituted 5' End mRNA Cap Analogues.

Paulina Pietrow, Aleksandra Ferenc-Mrozek, Karolina Piecyk, Elzbieta Bojarska, Edward Darzynkiewicz, Marzena Jankowska-Anyszka

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Paulina PietrowFaculty of Chemistry, University of Warsaw, 02-093 Warsaw, Poland.
Aleksandra Ferenc-MrozekDivision of Biophysics, Institute of Experimental Physics, Faculty of Physics and Centre of New Technologies, University of Warsaw, 02-097 Warsaw, Poland.
Karolina PiecykFaculty of Chemistry, University of Warsaw, 02-093 Warsaw, Poland.
Elzbieta BojarskaDivision of Biophysics, Institute of Experimental Physics, Faculty of Physics and Centre of New Technologies, University of Warsaw, 02-097 Warsaw, Poland.
Edward DarzynkiewiczDivision of Biophysics, Institute of Experimental Physics, Faculty of Physics and Centre of New Technologies, University of Warsaw, 02-097 Warsaw, Poland.
Marzena Jankowska-AnyszkaFaculty of Chemistry, University of Warsaw, 02-093 Warsaw, Poland.
University of Warsaw · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

mRNA degradation is a key mechanism of gene expression regulation. In the 3' → 5' decay pathway, mRNA is degraded by the exosome complex and the resulting cap dinucleotide or short-capped oligonucleotide is hydrolyzed mainly by a decapping scavenger enzyme (DcpS)-a member of the histidine triad family. The decapping mechanism is similar for DcpS from different species; however, their respective substrate specificities differ. In this paper, we describe experiments exploring DcpS activity from human (hDcps),

Identifiers

PMID31656932
PMCPMC6812366
OpenAlexW2979669562

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.