Evidence map›Paper›PMID 31656898›Full record

ArticleACS omega2019

Ring-Fused Diphenylchlorins as Potent Photosensitizers for Photodynamic Therapy Applications: In Vitro Tumor Cell Biology and in Vivo Chick Embryo Chorioallantoic Membrane Studies.

Bruno F O Nascimento, Mafalda Laranjo, Nelson A M Pereira, João Dias-Ferreira, Marta Piñeiro, Maria Filomena Botelho, Teresa M V D Pinho E Melo

Abstract read
In one paragraph

Article in ACS omega, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Ring-fused chlorin-enhanced photodynamic therapy for effective cell death induction in endometrial cancer.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025
    Article
  3. Article
  4. Review
  5. Applications of Photodynamic Therapy in Endometrial Diseases.Bioengineering (Basel, Switzerland) · 2022
    Review
  6. Ring-FusedFrontiers in chemistry · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Bruno F O NascimentoCQC and Department of Chemistry, University of Coimbra, 3004-535 Coimbra, Portugal.
Mafalda LaranjoBiophysics Institute and Institute for Clinical and Biomedical Research (iCBR), area of Environment Genetics and Oncobiology (CIMAGO), Faculty of Medicine and CNC.IBILI Consortium, University of Coimbra, 3004-548 Coimbra, Portugal.
Nelson A M PereiraCQC and Department of Chemistry, University of Coimbra, 3004-535 Coimbra, Portugal.
João Dias-FerreiraBiophysics Institute and Institute for Clinical and Biomedical Research (iCBR), area of Environment Genetics and Oncobiology (CIMAGO), Faculty of Medicine and CNC.IBILI Consortium, University of Coimbra, 3004-548 Coimbra, Portugal.
Marta PiñeiroCQC and Department of Chemistry, University of Coimbra, 3004-535 Coimbra, Portugal.
Maria Filomena BotelhoBiophysics Institute and Institute for Clinical and Biomedical Research (iCBR), area of Environment Genetics and Oncobiology (CIMAGO), Faculty of Medicine and CNC.IBILI Consortium, University of Coimbra, 3004-548 Coimbra, Portugal.
Teresa M V D Pinho E MeloCQC and Department of Chemistry, University of Coimbra, 3004-535 Coimbra, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ring-fused diphenylchlorins as potent low-dose photosensitizers for photodynamic therapy of bladder carcinoma and esophageal adenocarcinoma are described. All studied molecules were very active against HT1376 urinary bladder carcinoma and OE19 esophageal adenocarcinoma cell lines, showing IC

Identifiers

PMID31656898
PMCPMC6811853

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.