Evidence map›Paper›PMID 31656691›Full record

ArticleTremor and other hyperkinetic movements (New York, N.Y.)2019

Anti-CV2/CRMP5 Paraneoplastic Chorea Effectively Managed with Intravenous Amantadine.

Jongmok Ha, Boo Suk Na, Jong Hyeon Ahn, Minkyeong Kim, Jae Woo Kim, Jae Hyeok Lee, Jin Whan Cho, Ji Sun Kim, Jinyoung Youn

Open access · greenAbstract readCase Reports
In one paragraph

Article in Tremor and other hyperkinetic movements (New York, N.Y.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. MR Imaging Findings in a Large Population of Autoimmune Encephalitis.AJNR. American journal of neuroradiology · 2023
    Article
  6. Article
  7. Paraneoplastic Chorea Managed with Intravenous Amantadine.Tremor and other hyperkinetic movements (New York, N.Y.) · 2019
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Jongmok HaDepartment of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, KR.
Boo Suk NaDepartment of Neurology, Dongshin Hospital, Seoul, KR.
Jong Hyeon AhnDepartment of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, KR.
Minkyeong KimDepartment of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, KR.
Jae Woo KimDepartment of Neurology, Dong-A University College of Medicine, Busan, KR.
Jae Hyeok LeeDepartment of Neurology, Pusan National University Yangsan Hospital, Yangsan, KR.
Jin Whan ChoDepartment of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, KR.
Ji Sun KimDepartment of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, KR.
Jinyoung YounDepartment of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, KR.
Sungkyunkwan University · KRSamsung Medical Center · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Paraneoplastic chorea is typically a subacute progressive hyperkinetic movement disorder. The mainstay of treatment is managing the underlying neoplasm. However, the clinical course may be variable, and effective symptomatic management can precede the start of cancer treatment. Case report: A 63-year-old man presented with insidious onset, slowly progressive generalized chorea for 1 year, later diagnosed as anti-CV2/CRMP5 autoantibody positive paraneoplastic chorea. His chorea was markedly improved with intravenous amantadine. Discussion: In patients with anti-CV2/CRMP5 autoantibody-related chorea, sequential follow-up of brain magnetic resonance imaging reveals progression from active inflammation to atrophy. Our report highlights the efficacy of intravenous amantadine in paraneoplastic chorea.

Indexed as

Administration, IntravenousAmantadineAutoantibodiesCarrier ProteinsChoreaDopamine AgentsHumansHydrolasesMaleMicrotubule-Associated ProteinsMiddle AgedTreatment OutcomeAmantadineAutoantibodiesBMPER protein, humanCarrier ProteinsDopamine AgentsDPYSL5 protein, humanHydrolasesMicrotubule-Associated ProteinsautoimmunechoreaCRMP5CV2Paraneoplastic

Identifiers

PMID31656691
PMCPMC6790010
OpenAlexW2999493862

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.