ArticleJournal of thoracic disease2019
Peri-operative risk factors for in-hospital mortality in acute type A aortic dissection.
Article in Journal of thoracic disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Machine learning-based prediction of 1-year mortality risk after off-pump coronary artery bypass grafting.Journal of thoracic disease · 2026Article
- A Comprehensive Review of Acute Type A Aortic Dissection: Epidemiology, Classification, Management Strategies, Mortality Risk Assessment, and Ethical Considerations for Patients who Refuse Blood Transfusions.Reviews in cardiovascular medicine · 2025Review
- Prognostic factors and outcomes of acute type A aortic dissection: a retrospective clinical study.Journal of thoracic disease · 2025Article
- Mortality in orthopedic patients: a retrospective review of 333 medical records.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025Article
- An acute aortic dissection prognostic score for predicting early in-hospital mortality in acute thoracic aortic dissection.American heart journal plus : cardiology research and practice · 2025Article
- External validation of the German Registry for Acute Aortic Dissection Type A score in patients undergoing surgery for acute type A aortic dissection.JTCVS open · 2025Article
- Association of troponin I and macrophages in cardiac tamponade with Stanford type A aortic dissection.Heliyon · 2023Article
- Analysis of risk factors for postoperative mortality in acute type A aortic dissection patients under different critical levels.Scientific reports · 2023Article
- Article
- Differences among sexes in presentation and outcomes in acute type A aortic dissection repair.The Journal of thoracic and cardiovascular surgery · 2023Article
- Prediction of in-hospital death following acute type A aortic dissection.Frontiers in public health · 2023Article
- Clinical Features of Aortic Dissection in the Emergency Department: A Single-center Experience from South China.The western journal of emergency medicine · 2022Article
- Risk factors for 30-day mortality in patients who received DeBakey type I aortic dissection repair surgery.Journal of cardiothoracic surgery · 2021Article
- Factors Associated with In-Hospital Mortality in Acute Care Hospital Settings: A Prospective Observational Study.International journal of environmental research and public health · 2020Observational
- Perioperative risk factors for delayed extubation after acute type A aortic dissection surgery.Journal of thoracic disease · 2020Article
- Efficacy of interleukin-6 in combination with D-dimer in predicting early poor postoperative prognosis after acute stanford type a aortic dissection.Journal of cardiothoracic surgery · 2020Article
- Study on preoperative treatment of acute Type-A aortic dissection with endotracheal intubation combined with deep analgesia and sedation.Pakistan journal of medical sciencesArticle
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Authors and funding
9 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundAcute type A aortic dissection (TAAD) is cardiovascular emergency and requires surgical interventions. In-hospital mortality rate of surgical-treated TAAD patients remains high. We aim to examine the prognostic implications of peri-operative parameters to identify high-risk patient for in-hospital mortality.
methodsA total of 264 surgically treated TAAD patients were included in this study. The association between in-hospital mortality and peri-operative parameters were examined.
resultsThirty patients (11.36%) died during hospitalization. Patients with higher Apache II score had a significantly higher rate of in-hospital mortality when compared with patients scored ≤20 in unadjusted model [Score 21-25: HR =12.9 (1.7-100.8), P=0.0148; Score >25: HR =94.5 (12.6-707.6), P<0.0001]. Patients with Sbp >120 mmHg, Cr >200 mmol/L (both at admission and after surgery), BUN >8.2 mmol/L (both at admission and after surgery), AST >80 µ/L, aortic cross-clamping time >120 min and cardiopulmonary bypass time (CPBT) >230 min were also significantly related to higher rate of in-hospital mortality in univariate analysis. In multivariable analysis, APACHE II score [Score 21-25: HR =9.5 (1.2-74.4), P=0.032; Score >25: HR =51.0 (6.7-387.7), P=0.0001], AST >80 µmol/L [HR =2.3 (1.1-4.8), P=0.0251], aortic cross-clamping time >120 min (HR =2.9 (1.1-7.7), P=0.0315) remained significant in predicting TAAD in-hospital mortality.
conclusionsAPACHE II score could be a useful tool to predict TAAD in-hospital mortality. AST >80 µ/L and aortic cross-clamping time >120 min were also independent predictors.
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