ArticleF1000Research2019
Determinants of drug entry into the developing brain.
Article in F1000Research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07316387 (Neurobehavioral Development in Toddlers and Preschoolers in Relation to Prenatal Exposure of Mild Analgesics), which is not on this map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neurobehavioral Development in Toddlers and Preschoolers in Relation to Prenatal Exposure of Mild Analgesics
Who cites it
18 citing papers in PubMed, 74 citations in OpenAlex.
- Paracetamol, its metabolites, and their transfer between maternal circulation and fetal brain in mono- and combination therapies.Pharmacological reports : PR · 2025Article
- Associations of maternal blood biomarkers of prenatal APAP exposure with placental gene expression and child attention deficit hyperactivity disorder.Nature. Mental health · 2025Article
- ABC Efflux Transporters and Solute Carriers in the Early Developing Brain of a Marsupial Monodelphis domestica (South American Gray Short-Tailed Opossum).The Journal of comparative neurology · 2024Article
- Entry of cannabidiol into the fetal, postnatal and adult rat brain.Cell and tissue research · 2024Article
- Effects of paracetamol/acetaminophen on the expression of solute carriers (SLCs) in late-gestation fetal rat brain, choroid plexus and the placenta.Experimental physiology · 2024Article
- Paracetamol use in pregnancy: Not as safe as we may think?Acta obstetricia et gynecologica Scandinavica · 2023Article
- Developmental changes in the extent of drug binding to rat plasma proteins.Scientific reports · 2023Article
- The choroid plexus: a missing link in our understanding of brain development and function.Physiological reviews · 2023Review
- Age dependent contribution of entry via the CSF to the overall brain entry of small and large hydrophilic markers.Fluids and barriers of the CNS · 2022Article
- Entry of the antipsychotic drug, olanzapine, into the developing rat brain in mono- and combination therapies.F1000Research · 2022Article
- Lithium administered to pregnant, lactating and neonatal rats: entry into developing brain.Fluids and barriers of the CNS · 2021Article
- Paracetamol use during pregnancy - a call for precautionary action.Nature reviews. Endocrinology · 2021Review
- Efflux transporters in rat placenta and developing brain: transcriptomic and functional response to paracetamol.Scientific reports · 2021Article
- Ways to Address Perinatal Mast Cell Activation and Focal Brain Inflammation, including Response to SARS-CoV-2, in Autism Spectrum Disorder.Journal of personalized medicine · 2021Review
- Transfer of rhodamine-123 into the brain and cerebrospinal fluid of fetal, neonatal and adult rats.Fluids and barriers of the CNS · 2021Article
- Entry of antiepileptic drugs (valproate and lamotrigine) into the developing rat brain.F1000Research · 2021Article
- Effects of paracetamol (acetaminophen) on gene expression and permeability properties of the rat placenta and fetal brain.F1000Research · 2020Article
- Determinants of drug entry into the developing brain.F1000Research · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.