Evidence map›Paper›PMID 31656582›Full record

ReviewF1000Research2019

Recent advances in the understanding of Nipah virus immunopathogenesis and anti-viral approaches.

Rodolphe Pelissier, Mathieu Iampietro, Branka Horvat

Open access · goldAbstract readReview
In one paragraph

Review in F1000Research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 51 citations in OpenAlex.

  1. Article
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  11. Viruses · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Rodolphe Pelissier *International Center for Infectiology Research-CIRI, Immunobiology of Viral Infections team, Inserm U1111, CNRS, UMR5308, University of Lyon, Ecole Normale Supérieure de Lyon, France.
Mathieu Iampietro *International Center for Infectiology Research-CIRI, Immunobiology of Viral Infections team, Inserm U1111, CNRS, UMR5308, University of Lyon, Ecole Normale Supérieure de Lyon, France.
Branka HorvatInternational Center for Infectiology Research-CIRI, Immunobiology of Viral Infections team, Inserm U1111, CNRS, UMR5308, University of Lyon, Ecole Normale Supérieure de Lyon, France.ORCID 0000-0003-0578-7765
Université Claude Bernard Lyon 1 · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nipah virus (NiV) is a highly lethal zoonotic paramyxovirus that emerged at the end of last century as a human pathogen capable of causing severe acute respiratory infection and encephalitis. Although NiV provokes serious diseases in numerous mammalian species, the infection seems to be asymptomatic in NiV natural hosts, the fruit bats, which provide a continuous virus source for further outbreaks. Consecutive human-to-human transmission has been frequently observed during outbreaks in Bangladesh and India. NiV was shown to interfere with the innate immune response and interferon type I signaling, restraining the anti-viral response and permitting viral spread. Studies of adaptive immunity in infected patients and animal models have suggested an unbalanced immune response during NiV infection. Here, we summarize some of the recent studies of NiV pathogenesis and NiV-induced modulation of both innate and adaptive immune responses, as well as the development of novel prophylactic and therapeutic approaches, necessary to control this highly lethal emerging infection.

Indexed as

Adaptive ImmunityImmunity, InnateAnimalsBangladeshHenipavirus InfectionsHumansIndiaNipah Virusadaptive immunityanimal modelscontra-measuresinnate immunityNipah viruspathogenesis

Identifiers

PMID31656582
PMCPMC6798321
OpenAlexW2980355865

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.