Evidence map›Paper›PMID 31656365›Full record

ArticleProceedings of SPIE--the International Society for Optical Engineering2008

Single molecule photophysics near metallic nanostructures.

Jian Zhang, Yi Fu, Krishanu Ray, Mustafa H Chowdhury, Henryk Szmacinski, Kazimierz Nowaczyk, Joseph R Lakowicz

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of SPIE--the International Society for Optical Engineering, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jian ZhangCenter for Fluorescence Spectroscopy, University of Maryland School of Medicine, Department of Biochemistry and Molecular Biology, 725 West Lombard Street, Baltimore, MD 21201.
Yi FuCenter for Fluorescence Spectroscopy, University of Maryland School of Medicine, Department of Biochemistry and Molecular Biology, 725 West Lombard Street, Baltimore, MD 21201.
Krishanu RayCenter for Fluorescence Spectroscopy, University of Maryland School of Medicine, Department of Biochemistry and Molecular Biology, 725 West Lombard Street, Baltimore, MD 21201.
Mustafa H ChowdhuryCenter for Fluorescence Spectroscopy, University of Maryland School of Medicine, Department of Biochemistry and Molecular Biology, 725 West Lombard Street, Baltimore, MD 21201.
Henryk SzmacinskiCenter for Fluorescence Spectroscopy, University of Maryland School of Medicine, Department of Biochemistry and Molecular Biology, 725 West Lombard Street, Baltimore, MD 21201.
Kazimierz NowaczykCenter for Fluorescence Spectroscopy, University of Maryland School of Medicine, Department of Biochemistry and Molecular Biology, 725 West Lombard Street, Baltimore, MD 21201.
Joseph R LakowiczCenter for Fluorescence Spectroscopy, University of Maryland School of Medicine, Department of Biochemistry and Molecular Biology, 725 West Lombard Street, Baltimore, MD 21201.
University of Maryland, Baltimore · US

Funding

WHO'S WHO IN FLUORESCENCEP41RR008119 · NCRR · UNIVERSITY OF MARYLAND BALTIMORE · PI BASKAKOV, ILIA V · 1993 to 2006
$7.4M
NCRR NIH HHS P41 RR008119
6 · The paper itself

Abstract

Metal-enhanced fluorescence (MEF) is useful in single molecule detection (SMD) by increasing the photostability, brightness and increase in radiative decay rates of fluorophores. We have investigated MEF from an individual fluorophore tethered to a single silver nanoparticle and also a single fluorophore between a silver dimer. The fluorescence lifetime results revealed a near-field interaction mechanism of fluorophore with the metal particle. Finite-difference time-domain (FDTD) calculations were employed to study the distribution of electric field near the metal monomer and dimer. The coupling effect of metal particles on the fluorescence enhancement was studied. We have also investigated the photophysics of FRET near metal nanoparticles and our preliminary results suggest an enhanced FRET efficiency in the presence of a metal nanoparticle. In total, our results demonstrate improved detectability at the single molecule level for a variety of fluorophores and quantum dots in proximity to the silver nanoparticles due to the near-field metal-fluorophore interactions.

Indexed as

finite-difference time-domain (FDTD)fluorescence intensityFRETlifeimtmetal-enhanced fluorescence (MEF)metal nanoparticleMie theoryphotoblinkingphotostabilitysingle molecule detection (SMD)

Identifiers

PMID31656365
PMCPMC6813999
OpenAlexW2032401335

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.