Evidence map›Paper›PMID 31656362›Full record

ArticleChemometrics and intelligent laboratory systems : an international journal sponsored by the Chemometrics Society2019

BiMM forest: A random forest method for modeling clustered and longitudinal binary outcomes.

Jaime Lynn Speiser, Bethany J Wolf, Dongjun Chung, Constantine J Karvellas, David G Koch, Valerie L Durkalski

Abstract read
In one paragraph

Article in Chemometrics and intelligent laboratory systems : an international journal sponsored by the Chemometrics Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
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  12. Review
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  14. Predicting Future Mobility Limitation in Older Adults: A Machine Learning Analysis of Health ABC Study Data.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022
    Article
  15. Article
  16. Article
  17. Prediction With Mixed Effects Models: A Monte Carlo Simulation Study.Educational and psychological measurement · 2021
    Article
  18. Article
  19. Article
  20. A New Random Forest Algorithm Based on Learning Automata.Computational intelligence and neuroscience · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jaime Lynn SpeiserDepartment of Biostatistical Sciences, Wake Forest School of Medicine, Winston-Salem, NC.
Bethany J WolfDepartment of Public Health Sciences, Medical University of South Carolina, Charleston, SC.
Dongjun ChungDepartment of Public Health Sciences, Medical University of South Carolina, Charleston, SC.
Constantine J KarvellasDivisions of Hepatology and Critical Care Medicine, University of Alberta, Edmonton, Canada.
David G KochDivision of Gastroenterology and Hepatology, Department of Medicine, Medical University of South Carolina, Charleston, SC.
Valerie L DurkalskiDepartment of Public Health Sciences, Medical University of South Carolina, Charleston, SC.

Funding

South Carolina Clinical & Translational Research Institute (SCTR)UL1TR001450 · NCATS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BRADY, KATHLEEN T., FLUME, PATRICK A · 2015 to 2024
$41.1M
A Multi-Center Study of Acute Liver Failure in AdultsU01DK058369 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI DURKALSKI, VALERIE L, FONTANA, ROBERT J · 2005 to 2019
$27.4M
Wake Forest Clinical and Translational Science AwardKL2TR001421 · NCATS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI MILLER, DAVID P · 2015 to 2023
$5.8M
Patient Resource CoreP60AR062755 · NIAMS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI KAMEN, DIANE L · 2012 to 2016
$5.8M
South Carolina Clinical & Translational Research Institute (SCTR)TL1TR001451 · NCATS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI FEGHALI-BOSTWICK, CAROL A. · 2015 to 2024
$4.6M
Statistical Models for Genetic Studies, Using Network and Integrative AnalysisR01GM122078 · NIGMS · OHIO STATE UNIVERSITY · PI CHUNG, DONGJUN · 2016 to 2020
$1.9M
Algorithms for Literature-Guided Multi-Platform Identification of Cancer SubtypesR21CA209848 · NCI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI CHUNG, DONGJUN, KELEMEN, LINDA E · 2016 to 2017
$358k
NCATS NIH HHS KL2 TR001421NCATS NIH HHS TL1 TR001451NCATS NIH HHS UL1 TR001450NCI NIH HHS R21 CA209848NIAMS NIH HHS P60 AR062755NIDDK NIH HHS U01 DK058369NIGMS NIH HHS R01 GM122078
6 · The paper itself

Abstract

Clustered binary outcomes and datasets with many predictor variables are frequently encountered in clinical research (e.g. longitudinal studies). Generalized linear mixed models (GLMMs) typically employed for clustered endpoints have challenges for some scenarios, particularly for complex datasets which contain many interactions among predictors and nonlinear predictors of outcome. We propose a new method called Binary Mixed Model (BiMM) forest, which combines random forest and GLMM methodology. BiMM forest offers a flexible and stable method which naturally models interactions among predictors and can be employed in the setting of clustered data. Simulation studies show that BiMM forest achieves similar or superior prediction accuracy compared to standard random forest, GLMMs and its tree counterpart (BiMM tree) for clustered binary outcomes. The method is applied to a real dataset from the Acute Liver Failure Study Group. BiMM forest offers an alternative method for modeling clustered binary outcomes which may be applied in myriad research settings.

Indexed as

clustered datalongitudinal datamixed effectsrandom forest

Identifiers

PMID31656362
PMCPMC6813794

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.