ArticleDevelopment and psychopathology2020
Developmental pathways to social anxiety and irritability: The role of the ERN.
Article in Development and psychopathology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 17 papers, 2 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Understanding irritability through the lens of self-regulatory control processes in children and adolescents: a systematic review.European child & adolescent psychiatry · 2025Pooled it
- Annual Research Review: What processes are dysregulated among emotionally dysregulated youth? - a systematic review.Journal of child psychology and psychiatry, and allied disciplines · 2025Pooled it
- Neural Responsivity to Unexpected Stimuli Moderates a Developmental Pathway to Anxiety: A Community-Sample Replication in Early Infancy and Childhood.medRxiv : the preprint server for health sciences · 2026Article
- Inhibition-related connectivity predicts irritability risk and resilience across early adolescence.Social cognitive and affective neuroscience · 2026Article
- Adolescent cognitive control processing is associated with anxiety in young adulthood during the COVID-19 pandemic.Cognitive, affective & behavioral neuroscience · 2025Article
- Maternal Social Phobia, but not Generalized Anxiety, Symptoms Interact with Early Childhood Error-Related Negativity to Prospectively Predict Child Anxiety Symptoms.Research on child and adolescent psychopathology · 2025Article
- Emotion Regulation Moderates the Prospective Association between ERN and Anxiety in Early Adolescence: An Age-Specific Moderation of Cognitive Reappraisal but not Expressive Suppression.Research on child and adolescent psychopathology · 2025Article
- Error-related brain activity shapes the association between trait neuroticism and internalizing symptomatology in two tasks.International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2024Article
- Research hotspots and trends of neuroimaging in social anxiety: a CiteSpace bibliometric analysis based on Web of Science and Scopus database.Frontiers in behavioral neuroscience · 2024Review
- Changes in Behavior and Neural Dynamics across Adolescent Development.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Cross-sectional and Longitudinal Associations of Anxiety and Irritability With Adolescents' Neural Responses to Cognitive Conflict.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2023Article
- Translating Big Data to Clinical Outcomes in Anxiety: Potential for Multimodal Integration.Current psychiatry reports · 2022Review
- Convergent neural correlates of prenatal exposure to air pollution and behavioral phenotypes of risk for internalizing and externalizing problems: Potential biological and cognitive pathways.Neuroscience and biobehavioral reviews · 2022Review
- Developmental Changes in the Association Between Cognitive Control and Anxiety.Child psychiatry and human development · 2022Article
- Temperamental risk for anxiety: emerging work on the infant brain and later neurocognitive development.Current opinion in behavioral sciences · 2022Article
- Neurocognitive Profiles in Adolescence Predict Subsequent Anxiety Trajectories During the COVID-19 Pandemic.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2022Article
- Amygdala Functional Connectivity and Negative Reactive Temperament at Age 4 Months.Journal of the American Academy of Child and Adolescent Psychiatry · 2021Article
Corrections and comments
- Erratum issued
Authors and funding
10 authors.
Funding
Abstract
Early behaviors that differentiate later biomarkers for psychopathology can guide preventive efforts while also facilitating pathophysiological research. We tested whether error-related negativity (ERN) moderates the link between early behavior and later psychopathology in two early childhood phenotypes: behavioral inhibition and irritability. From ages 2 to 7 years, children (n = 291) were assessed longitudinally for behavioral inhibition (BI) and irritability. Behavioral inhibition was assessed via maternal report and behavioral responses to novelty. Childhood irritability was assessed using the Child Behavior Checklist. At age 12, an electroencephalogram (EEG) was recorded while children performed a flanker task to measure ERN, a neural indicator of error monitoring. Clinical assessments of anxiety and irritability were conducted using questionnaires (i.e., Screen for Child Anxiety Related Disorders and Affective Reactivity Index) and clinical interviews. Error monitoring interacted with early BI and early irritability to predict later psychopathology. Among children with high BI, an enhanced ERN predicted greater social anxiety at age 12. In contrast, children with high childhood irritability and blunted ERN predicted greater irritability at age 12. This converges with previous work and provides novel insight into the specificity of pathways associated with psychopathology.
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